Animal models of abdominal aortic aneurysm and their role in furthering management of human disease

A Trollope, JV Moxon, CS Moran, J Golledge - Cardiovascular Pathology, 2011 - Elsevier
Abdominal aortic aneurysm is a common degenerative disorder associated with sudden
death due to aortic rupture. Current therapy is limited to open surgical repair of the aorta or …

Translational relevance and recent advances of animal models of abdominal aortic aneurysm

J Sénémaud, G Caligiuri, H Etienne… - … , and vascular biology, 2017 - Am Heart Assoc
Human abdominal aortic aneurysm (AAA) pathophysiology is not yet completely understood.
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …

Medical management of small abdominal aortic aneurysms

BT Baxter, MC Terrin, RL Dalman - Circulation, 2008 - Am Heart Assoc
Abdominal aortic aneurysm is a common condition that may be lethal when it is
unrecognized. Current guidelines suggest repair as the aneurysm diameter reaches 5.0 to …

Operative repair for aortic aneurysms: the gold standard

CK Zarins, EJ Harris Jr - Journal of Endovascular Therapy, 1997 - journals.sagepub.com
Surgical treatment of abdominal aortic aneurysm (AAA) is being challenged by newer,
minimally invasive therapies. Such new treatment strategies will need to prove themselves …

[HTML][HTML] Paradigm shifts in the treatment of abdominal aortic aneurysm: trends in 721 patients between 1996 and 2008

FC Albuquerque Jr, BH Tonnessen, RE Noll Jr… - Journal of vascular …, 2010 - Elsevier
OBJECTIVE: This study evaluated longitudinal trends in abdominal aortic aneurysm (AAA)
management after later-generation endografts became available. METHODS: We …

[HTML][HTML] Abdominal aortic aneurysm formation with a focus on vascular smooth muscle cells

G Qian, O Adeyanju, A Olajuyin, X Guo - Life, 2022 - mdpi.com
Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease

MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …

[HTML][HTML] Editor's Choice–pharmaceutical management of small abdominal aortic aneurysms: a systematic review of the clinical evidence

VBC Kokje, JF Hamming, JHN Lindeman - European Journal of Vascular …, 2015 - Elsevier
Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

Surgery for small asymptomatic abdominal aortic aneurysms

G Filardo, JT Powell, MAM Martinez… - Cochrane Database of …, 2015 - cochranelibrary.com
Background An abdominal aortic aneurysm (AAA) is an abnormal ballooning of the major
abdominal artery. Some AAAs present as emergencies and require surgery; others remain …

[HTML][HTML] Abdominal aortic aneurysm: A comprehensive review

S Aggarwal, A Qamar, V Sharma… - Experimental & Clinical …, 2011 - ncbi.nlm.nih.gov
An arterial aneurysm is defined as a focal dilation of a blood vessel with respect to the
original artery. The risk of abdominal aortic aneurysms (AAAs) increases dramatically in the …