Recent technological advances have made it possible to decode DNA methylomes at single-
base-pair resolution under various physiological conditions. Many aberrant or differentially …

DNA methylation occurring on the 5 position of the pyrimidine ring of cytosines in the context
of the dinucleotide sequence CpG forms one of the multiple layers of epigenetic …

DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …

DNA methylation at position C5 of the pyrimidine ring of cytosine in mammalian genomes
has received a great deal of research interest due to its importance in many biological …

Background DNA methylation is thought to play an important role in the regulation of
mammalian gene expression, partly based on the observation that a lack of CpG island …

We have developed a strategy to introduce in vitro-methylated DNA into defined
chromosomal locations. Using this system, we examined the effects of methylation on …

Methylation of cytosine in CpG dinucleotides and histone lysine and arginine residues is a
chromatin modification that critically contributes to the regulation of genome integrity …

DNA methylation: A molecular lock Page 1 Dispatch R305 DNA methylation: A molecular lock
Zahava Siegfried and Howard Cedar In mammals, the promoters of expressed genes are …

DNA methylation is among the best studied epigenetic modifications and is essential to
mammalian development. Although the methylation status of most CpG dinucleotides in the …

Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …