Mechanisms of DNA methylation and demethylation in mammals
G Auclair, M Weber - Biochimie, 2012 - Elsevier
Cytosine methylation is an epigenetically propagated DNA modification that can modify how
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …
Deciphering the epigenetic code: an overview of DNA methylation analysis methods
Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …
profound implications in development, normal biology, and disease conditions in many …
[HTML][HTML] DNA methylation: a timeline of methods and applications
A Harrison, A Parle-McDermott - Frontiers in genetics, 2011 - frontiersin.org
DNA methylation is a biochemical process where a DNA base, usually cytosine, is
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …
Variations in DNA methylation patterns during the cell cycle of HeLa cells
SE Brown, MF Fraga, ICG Weaver, M Berdasco… - Epigenetics, 2007 - Taylor & Francis
DNA methylation has been viewed as a stable component of the epigenome, which is
established during development and fixed thereafter. We show here using nearest neighbor …
established during development and fixed thereafter. We show here using nearest neighbor …
The role of DNA methylation in gene regulation
PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
The addition of a methyl group to a DNA base is known as DNA methylation. Typically, this
occurs at the location of a cytosine proximal to a guanine base and is catalyzed by enzymes …
occurs at the location of a cytosine proximal to a guanine base and is catalyzed by enzymes …
DNA methylation has a local effect on transcription and histone acetylation
RA Irvine, IG Lin, CL Hsieh - Molecular and cellular biology, 2002 - Taylor & Francis
DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …
deacetylation and DNA methylation has been established. However, the transcriptional …
A diverse epigenetic landscape at human exons with implication for expression
DNA methylation is an important epigenetic marker associated with gene expression
regulation in eukaryotes. While promoter methylation is relatively well characterized, the role …
regulation in eukaryotes. While promoter methylation is relatively well characterized, the role …
DNA methylation‐mediated epigenetic control
A Rottach, H Leonhardt, F Spada - Journal of cellular …, 2009 - Wiley Online Library
During differentiation and development cells undergo dramatic morphological and functional
changes without any change in the DNA sequence. The underlying changes of gene …
changes without any change in the DNA sequence. The underlying changes of gene …
Genome-wide analysis of DNA methylation patterns
D Zilberman, S Henikoff - 2007 - journals.biologists.com
Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA
methylation has an important role in many aspects of biology, including development and …
methylation has an important role in many aspects of biology, including development and …
[HTML][HTML] DNA methylation and human disease
KD Robertson - Nature Reviews Genetics, 2005 - nature.com
DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …
regulating many cellular processes. These include embryonic development, transcription …