Mechanisms of DNA methylation and demethylation in mammals

G Auclair, M Weber - Biochimie, 2012 - Elsevier
Cytosine methylation is an epigenetically propagated DNA modification that can modify how
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …

Deciphering the epigenetic code: an overview of DNA methylation analysis methods

M Umer, Z Herceg - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …

[HTML][HTML] DNA methylation: a timeline of methods and applications

A Harrison, A Parle-McDermott - Frontiers in genetics, 2011 - frontiersin.org
DNA methylation is a biochemical process where a DNA base, usually cytosine, is
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …

Variations in DNA methylation patterns during the cell cycle of HeLa cells

SE Brown, MF Fraga, ICG Weaver, M Berdasco… - Epigenetics, 2007 - Taylor & Francis
DNA methylation has been viewed as a stable component of the epigenome, which is
established during development and fixed thereafter. We show here using nearest neighbor …

The role of DNA methylation in gene regulation

PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
The addition of a methyl group to a DNA base is known as DNA methylation. Typically, this
occurs at the location of a cytosine proximal to a guanine base and is catalyzed by enzymes …

DNA methylation has a local effect on transcription and histone acetylation

RA Irvine, IG Lin, CL Hsieh - Molecular and cellular biology, 2002 - Taylor & Francis
DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …

A diverse epigenetic landscape at human exons with implication for expression

M Singer, I Kosti, L Pachter… - Nucleic acids …, 2015 - academic.oup.com
DNA methylation is an important epigenetic marker associated with gene expression
regulation in eukaryotes. While promoter methylation is relatively well characterized, the role …

DNA methylation‐mediated epigenetic control

A Rottach, H Leonhardt, F Spada - Journal of cellular …, 2009 - Wiley Online Library
During differentiation and development cells undergo dramatic morphological and functional
changes without any change in the DNA sequence. The underlying changes of gene …

Genome-wide analysis of DNA methylation patterns

D Zilberman, S Henikoff - 2007 - journals.biologists.com
Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA
methylation has an important role in many aspects of biology, including development and …

[HTML][HTML] DNA methylation and human disease

KD Robertson - Nature Reviews Genetics, 2005 - nature.com
DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …