Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the
development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify …

Since elevated serum levels of trimethylamine N-oxide (TMAO) were first associated with
increased risk of cardiovascular disease (CVD), TMAO research among chronic diseases …

Trimethylamine N-oxide (TMAO) is a biologically active molecule and is a putative promoter
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …

Background Trimethylamine N‐oxide (TMAO) is a gut microbiota‐dependent metabolite of
dietary choline, L‐carnitine, and phosphatidylcholine‐rich foods. On the basis of …

Trimethylamine-N-oxide (TMAO) is the main diet-induced metabolite produced by the gut
microbiota, and it is mainly eliminated through renal excretion. TMAO has been correlated …

Abstract Purpose of Review Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent
metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was …

Aims The microbiome-derived metabolite trimethylamine-N-oxide (TMAO) has attracted
major interest and controversy both as a diagnostic biomarker and therapeutic target in …

ABSTRACT Background Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–
related metabolite, is associated with cardiovascular disease (CVD). However, major dietary …

There is increasing appreciation that changes in microbiome composition and function can
promote long-term susceptibility for cardiometabolic risk. Gut microbe-derived metabolites …

Trimethylamine-N-oxide (TMAO) is generated in a microbial-mammalian co-metabolic
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …