Background The purpose of the present study was to evaluate the effect of a new
angiotensin converting enzyme inhibitor perindopril on the formation of experimental …

AIMS: Angiotensin-converting enzyme (ACE) inhibitors have proven their ability to affect
vascular wall remodelling, in addition to their anti-hypertensive effects. The aim of this study …

Purpose: Pathologic remodeling of the extracellular matrix is a critical mechanism in the
development and progression of abdominal aortic aneurysms (AAAs). Although angiotensin …

The objective of this study was to trigger the formation of rat abdominal aortic aneurysm by
applying calcium chloride periarterially and then to detect the degree of prevention of …

The effects of ACE inhibition with perindopril on the atherosclerosis-induced impairment of
arterial flow were investigated via histopathologic studies, hemodynamics, and vascular …

BACKGROUND: The present experiments sought to determine whether cilostazol, a
selective inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase 3 …

Objective The purpose of this study was to establish a reliable, chronic model of abdominal
aortic aneurysm (AAA). Methods Wild-type 8-week-old C56BL/6 male mice (n= 120) were …

Background To create a novel procedure that will decrease the mortality of experimental
animals in the intraarterial infusion of elastase abdominal aortic aneurysm (AAA) model …

Objective This study tested the hypothesis that an experimental model of abdominal aortic
aneurysm in rabbits results in progressive enlargement when induced by a combination of …

OBJECTIVE: An ideal animal model of abdominal aortic aneurysm (AAA) is of great
importance for clarifying unknown complex mechanisms of the pathogenesis. We introduce …