Perfusion of the rat abdominal aorta with elastase induces abdominal aortic aneurysms
(AAA), in which the development of aortic dilatation correlates with the influx of inflammatory …

Background The purpose of this study was to introduce a novel, simple and effective
technique for creating a reliable rabbit model of abdominal aortic aneurysm (AAA) via a …

Background The inflammatory reaction is an important mechanism of pathogenesis of
abdominal aortic aneurysm (AAA). Artesunate (AS) has been found to have anti …

BACKGROUND: The purpose of the present study was to investigate whether tanshinone IIA
(Tan IIA), one of the major lipophilic components of Salvia miltiorrhiza Bunge, could inhibit …

PURPOSE: The objective of this study was to determine the possibility of creating a novel
animal model of abdominal aortic aneurysm (AAA) in rabbits by the periarterial application of …

Objective: Cystic medial degeneration (CMD) is a histologic abnormality that is common in
aortic diseases such as aortic dilation, aneurysm, or dissection. Although little is known …

BACKGROUND: Our aim was to establish a novel model of abdominal aortic aneurysms
(AAA) in mice using application of peri-adventitial elastase. METHODS: C57BL/6J male …

Aim. Observational studies in human patients and animal experiments suggested that statins
have a potential in slowing the growth of small abdominal aortic aneurysms (AAA). Our aim …

Background Although systemic hypertension is closely associated with aortic aneurysm (AA)
formation, there are many patients with AA without hypertension. In these patients, an …

Background. Abdominal aortic aneurysms (AAAs) involve an unfavorable balance between
the destruction and the repair of connective tissue proteins. The purpose of this study was to …