Objective: The effect of brief, prehypertensive therapy by angiotensin-converting enzyme
inhibition (ACEi) with perindopril on the structure and function of large arteries was studied …

Objective This study examined the influence of 3, 4-benzopyrene (BaP), a compound found
in cigarette smoke, on the formation of angiotensin II (Ang II)-induced abdominal aortic …

Background and Purpose Abdominal aortic aneurysm (AAA) is a degenerative disease with
irreversible and progressive dilation of the artery. But there are few options for efficacious …

This study investigated the effect of the angiotensin-converting enzyme (ACE) inhibitor
perindopril on left ventricular (LV) remodeling and cardiac function in rats with aortic …

The present work was designed to observe the early structural changes in the aortic wall in
Sprague-Dawley rats 1, 2 and 4 weeks after sinoaortic denervation (SAD). 2. Rats were …

Purpose: Tumor necrosis factor (TNF), interleukin 1 (IL-1), and matrix metalloproteases have
been noted to be elevated in human abdominal aortic aneurysms (AAAs) as compared with …

Previous findings vary regarding the timing and cause of elastin fiber degeneration in the
elastaseinduced rat abdominal aortic aneurysm model. We examined the timing and cause …

Aims: The renin–angiotensin system (RAS) plays an important role in the pathophysiology of
vascular diseases, especially as a mediator of inflammation and tissue remodelling …

OBJECTIVES:: To investigate (i) elastin degradation and the possible association between
proteolysis and inflammation in abdominal aortic aneurysm disease (AAA), and (ii) the …

Agents to inhibit the renin-angiotensin system have been reported to suppress the
progression of abdominal aortic aneurysm (AAA). However, the effects of calcium channel …