Purpose: It has been suggested that propranolol has unique effects that slow aneurysm
expansion by remodeling the structural proteins of the aorta. These effects are believed to …

Objective: Aortic dissection is a life-threatening disease. At present, the only therapeutic
strategies available are surgery and antihypertensive drugs. Moreover, the molecular …

Agents to inhibit the renin-angiotensin system have been reported to suppress the
progression of abdominal aortic aneurysm (AAA). However, the effects of calcium channel …

The aim of the present study was to evaluate the effect of overstimulation of β-adrenoceptors
on vascular inflammatory mediators. Wistar rats were treated with the β-adrenoceptor …

Abstract Objective Angiotensin (Ang) II type 1 receptor (AT1) activation is essential for the
development of exogenous Ang II-induced abdominal aortic aneurysms (AAAs) in …

Previous studies have indicated that AngII infusion promotes AAA incidence≈ 80% in male
hyperlipidemic mice but only≈ 10% in male normolipidemic mice. Conversely, AngII …

Background To determine whether all-trans retinoic acid (ATRA) can influence the
development of Angiotensin II (Ang II) induced experimental abdominal aortic aneurysms …

An abdominal aortic aneurysm (AAA) is an enlargement of the greatest artery in the body
defined as an increase in diameter of 1.5-fold. AAAs are common in the elderly population …

Purpose: Increased local production of matrix metalloproteinases (MMPs) is a potential
mechanism underlying structural protein degradation in abdominal aortic aneurysms (AAA) …

Abdominal aortic aneurysm (AAA) represents a debilitating vascular disease characterized
by aortic dilatation and wall rupture if it remains untreated. We aimed to determine the effects …