Pathophysiology of abdominal aortic aneurysm: Biomarkers and novel therapeutic targets

M Torres-Fonseca, M Galan, D Martinez-Lopez… - Clínica e Investigación …, 2019 - Elsevier
Abdominal aortic aneurysm (AAA) is a vascular pathology with a high rate of morbidity and
mortality and a prevalence that, in men over 65 years, can reach around 8%. In this disease …

Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients' management

J Golledge, PE Norman - Current opinion in cardiology, 2009 - journals.lww.com
Pathophysiology of abdominal aortic aneurysm relevant to imp... : Current Opinion in Cardiology
Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients' …

Novel insight into the pathobiology of abdominal aortic aneurysm and potential future treatment concepts

N Diehm, F Dick, T Schaffner, J Schmidli… - Progress in …, 2007 - Elsevier
The patient with abdominal aortic aneurysm (AAA) commonly is a nondiabetic, white man
with a history of smoking. Moreover, AAA represents a leading cause of death in elderly men …

Abdominal aortic aneurysm: novel mechanisms and therapies

FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …

[HTML][HTML] Novel biomarkers of abdominal aortic aneurysm disease: identifying gaps and dispelling misperceptions

D Moris, E Mantonakis, E Avgerinos… - BioMed Research …, 2014 - hindawi.com
Abdominal aortic aneurysm (AAA) is a prevalent and potentially life-threatening disease.
Early detection by screening programs and subsequent surveillance has been shown to be …

Meta-analysis and meta-regression analysis of biomarkers for abdominal aortic aneurysm

PW Stather, DA Sidloff, N Dattani… - Journal of British …, 2014 - academic.oup.com
Background Many studies have investigated the systemic and local expression of
biomarkers in patients with abdominal aortic aneurysm (AAA). The natural history of AAA …

Abdominal aortic aneurysm: pathogenesis and implications for management

J Golledge, J Muller, A Daugherty… - … , and vascular biology, 2006 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) affects approximately 5% of elderly men and is
responsible for a significant number of deaths in Western Countries. At present surgery by …

Review of current theories for abdominal aortic aneurysm pathogenesis

IM Nordon, RJ Hinchliffe, PJ Holt, IM Loftus… - …, 2009 - journals.sagepub.com
Atherosclerotic plaques are a feature of abdominal aortic aneurysms (AAAs).
Atherosclerosis and AAA appear to share similar risk factors. These observations have led to …

Cytokines and systemic biomarkers are related to the size of abdominal aortic aneurysms

D Flondell-Sité, B Lindblad, T Kölbel, A Gottsäter - Cytokine, 2009 - Elsevier
Objective: The etiology of abdominal aortic aneurysm (AAA) includes atherosclerotic,
inflammatory, immunological and coagulatory mechanisms. The aim of this study was to …

Understanding the pathogenesis of abdominal aortic aneurysms

H Kuivaniemi, EJ Ryer, JR Elmore… - Expert review of …, 2015 - Taylor & Francis
An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …