Computed Tomography Angiography Markers and Intraluminal Thrombus Morphology as Predictors of Abdominal Aortic Aneurysm Rupture

EM Arbănași, AV Mureșan, CM Coșarcă… - International Journal of …, 2022 - mdpi.com
Background: Abdominal aortic aneurysm (AAA) is a complex vascular disease characterized
by progressive and irreversible local dilatation of the aortic wall. Currently, the indication for …

[HTML][HTML] Challenges and opportunities in limiting abdominal aortic aneurysm growth

J Golledge, PE Norman, MP Murphy… - Journal of vascular …, 2017 - Elsevier
Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

The association of biomarkers of inflammation and extracellular matrix degradation with the risk of abdominal aortic aneurysm: the ARIC study

W Tang, L Yao, RC Hoogeveen, A Alonso… - …, 2019 - journals.sagepub.com
Animal and human laboratory studies suggest that the pathogenesis of abdominal aortic
aneurysms (AAAs) involves inflammation and degradation and remodeling of the …

Research advances in drug therapy for abdominal aortic aneurysms over the past five years: An updated narrative review

R Li, Y Liu, J Jiang - International Journal of Cardiology, 2023 - Elsevier
Background Abdominal aortic aneurysms (AAA) rupture can lead to patient death. Surgical
treatment is currently the optimal treatment for AAA with large diameter (≥ 50 mm). For AAA …

Aneurysm-Express: human abdominal aortic aneurysm wall expression in relation to heterogeneity and vascular events–rationale and design

R Hurks, IE Hoefer, A Vink, JPPM De Vries… - European Surgical …, 2010 - karger.com
Objective: Elective repair of abdominal aortic aneurysms (AAA) is associated with significant
morbidity and mortality. Large amounts of AAA tissue are necessary to assess heterogeneity …

[HTML][HTML] Editor's choice–pharmaceutical management of small abdominal aortic aneurysms: a systematic review of the clinical evidence

VBC Kokje, JF Hamming, JHN Lindeman - European Journal of Vascular …, 2015 - Elsevier
Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

Lack of an effective drug therapy for abdominal aortic aneurysm

J Golledge, JV Moxon, TP Singh… - Journal of internal …, 2020 - Wiley Online Library
Abdominal aortic aneurysm (AAA) rupture is a common cause of death in adults. Current
AAA treatment is by open surgical or endovascular aneurysm repair. Rodent model and …

Basic research studies to understand aneurysm disease.

AM Boddy, GM Lenk, JH Lillvis, J Nischan… - Drug news & …, 2008 - europepmc.org
Abdominal aortic aneurysm (AAA) is a complex multifactorial disease with life-threatening
implications. Aneurysms typically have no signs or symptoms, and rupture of AAA has a high …

Abdominal aortic aneurysm: An update

J Chuen, M Theivendran - Australian Journal of General …, 2018 - search.informit.org
Background: Abdominal aortic aneurysm (AAA) remains one of the hallmark pathologies in
vascular surgery and an area of intense research interest. Treatment options have …

Abdominal aortic aneurysm pathomechanics: current understanding and future directions

EMC Kemmerling, RA Peattie - … , cellular, and tissue engineering of the …, 2018 - Springer
Abdominal aortic aneurysms (AAAs) are permanent, local expansions of the abdominal
segment of the aorta that can potentially be fatal if progressing to rupture. AAAs are rarely …