[PDF][PDF] Novel aspects of PPARα‐mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study
Peroxisome proliferator‐activated receptor‐α (PPARα) is a major transcriptional regulator of
lipid metabolism. It is activated by diverse chemicals such as fatty acids (FAs) and regulates …
lipid metabolism. It is activated by diverse chemicals such as fatty acids (FAs) and regulates …
Peroxisome proliferator-activated receptor α mediates the effects of high-fat diet on hepatic gene expression
Peroxisome proliferator-activated receptors (PPARs) are transcription factors involved in the
regulation of numerous metabolic processes. The PPARα isotype is abundant in liver and …
regulation of numerous metabolic processes. The PPARα isotype is abundant in liver and …
Comprehensive Analysis of PPARα‐Dependent Regulation of Hepatic Lipid Metabolism by Expression Profiling
M Rakhshandehroo, LM Sanderson… - PPAR …, 2007 - Wiley Online Library
PPARα is a ligand‐activated transcription factor involved in the regulation of nutrient
metabolism and inflammation. Although much is already known about the function of PPARα …
metabolism and inflammation. Although much is already known about the function of PPARα …
Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium
K Oshida, N Vasani, RS Thomas, D Applegate… - PloS one, 2015 - journals.plos.org
The nuclear receptor family member peroxisome proliferator-activated receptor α (PPARα) is
activated by therapeutic hypolipidemic drugs and environmentally-relevant chemicals to …
activated by therapeutic hypolipidemic drugs and environmentally-relevant chemicals to …
Comparative analysis of gene regulation by the transcription factor PPARα between mouse and human
Background Studies in mice have shown that PPARα is an important regulator of hepatic
lipid metabolism and the acute phase response. However, little information is available on …
lipid metabolism and the acute phase response. However, little information is available on …
PPARs as metabolic regulators in the liver: lessons from liver-specific PPAR-null mice
Y Wang, T Nakajima, FJ Gonzalez… - International journal of …, 2020 - mdpi.com
Peroxisome proliferator-activated receptor (PPAR) α, β/δ, and γ modulate lipid homeostasis.
PPARα regulates lipid metabolism in the liver, the organ that largely controls whole-body …
PPARα regulates lipid metabolism in the liver, the organ that largely controls whole-body …
[HTML][HTML] Hepatic lipid homeostasis by peroxisome proliferator-activated receptor gamma 2
YK Lee, JE Park, M Lee, JP Hardwick - Liver research, 2018 - Elsevier
Peroxisome proliferator-activated receptor gamma (PPARγ or PPARG) is a ligand-activated
transcription factor belonging to the nuclear hormone receptor superfamily. It plays a master …
transcription factor belonging to the nuclear hormone receptor superfamily. It plays a master …
Changes in liver PPARα mRNA expression in response to two levels of high-safflower-oil diets correlate with changes in adiposity and serum leptin in rats and mice
SC Hsu, C Huang - The Journal of nutritional biochemistry, 2007 - Elsevier
The ligand-dependent transcription factor peroxisome proliferator-activated receptor α
(PPARα) is known to be activated by common fatty acids and to regulate the expression of …
(PPARα) is known to be activated by common fatty acids and to regulate the expression of …
Transcriptional profiling reveals divergent roles of PPARα and PPARβ/δ in regulation of gene expression in mouse liver
LM Sanderson, MV Boekschoten… - Physiological …, 2010 - journals.physiology.org
Little is known about the role of the transcription factor peroxisome proliferator-activated
receptor (PPAR) β/δ in liver. Here we set out to better elucidate the function of PPARβ/δ in …
receptor (PPAR) β/δ in liver. Here we set out to better elucidate the function of PPARβ/δ in …
Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics
LM Sanderson, PJ de Groot, GJEJ Hooiveld, A Koppen… - PloS one, 2008 - journals.plos.org
Background The effect of dietary fats on human health and disease are likely mediated by
changes in gene expression. Several transcription factors have been shown to respond to …
changes in gene expression. Several transcription factors have been shown to respond to …