Non-alcoholic fatty liver disease (NAFLD) is an emerging global disease with increasing
prevalence. However, the mechanism of NAFLD development is not fully understood. To …

Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic
syndrome. Insulin resistance (IR) is important in the development and progression of …

Nuclear factor erythroid 2‐related factor 2 (Nrf2) is reportedly involved in hepatic lipid
metabolism, but the results are contradictory, and the underlying mechanism remains …

Mice lacking the transcription factor NF-E2 p45-related factor 2 (Nrf2) develop more severe
nonalcoholic steatohepatitis (NASH), with cirrhosis, than wild-type (Nrf2+/+) mice when fed a …

Abstract Background and Aim: Hepatic excessive iron may play a role in the pathogenesis of
non‐alcoholic steatohepatitis (NASH). Nrf2 is a master regulator of antioxidative responses …

Nonalcoholic fatty liver disease (NAFLD) is a progressive liver disease with ever‐growing
incidence in the industrialized world. It starts with the simple accumulation of lipids in the …

Nuclear factor erythroid-2 related factor 2 (Nrf2) plays a pivotal role in cytoprotection against
both endogenous and exogenous stresses. Here, we establish a novel molecular link …

Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in Western countries and has
become a serious public health concern. Although Western-style dietary patterns …

Aims: The nuclear receptor liver X receptor-α (LXRα) stimulates lipogenesis, leading to
steatosis. Nuclear factor erythroid-2-related factor-2 (Nrf2) contributes to cellular defense …

Background The transcription factor nuclear factor-E2-related factor-2 (Nrf2) inhibits lipid
accumulation and oxidative stress in the liver by interfering with lipogenic pathways and …