Cryptococcus neoformans capsular polysaccharides form branched and complex filamentous networks viewed by high-resolution microscopy

GRS Araujo, GN Fontes, D Leão, GM Rocha… - Journal of structural …, 2016 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections in
immunocompromised individuals. Its main virulence factor is an extracellular polysaccharide …

Exploring Cryptococcus neoformans capsule structure and assembly with a hydroxylamine-armed fluorescent probe

CJ Crawford, RJB Cordero, L Guazzelli… - Journal of Biological …, 2020 - ASBMB
Chemical biology is an emerging field that enables the study and manipulation of biological
systems with probes whose reactivities provide structural insights. The opportunistic fungal …

Ultrastructural Study of Cryptococcus neoformans Surface During Budding Events

GRS Araújo, CL Alcantara, N Rodrigues… - Frontiers in …, 2021 - frontiersin.org
Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections in
immunocompromised individuals. It is surrounded by three concentric structures that …

Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture

MP Wear, E Jacobs, S Wang, SA McConnell… - Journal of Biological …, 2022 - ASBMB
The polysaccharide capsule of fungal pathogen Cryptococcus neoformans is a critical
virulence factor that has historically evaded complete characterization. Cryptococcal …

The capsular dynamics of Cryptococcus neoformans

D McFadden, O Zaragoza, A Casadevall - TRENDS in Microbiology, 2006 - cell.com
Cryptococcus neoformans is a soil-dwelling fungus that causes life-threatening illness in
immunocompromised individuals and latently infects many healthy individuals. C …

Molecular architecture of the Cryptococcus neoformans capsule

MA Gates, P Thorkildson, TR Kozel - Molecular microbiology, 2004 - Wiley Online Library
Many microbes are surrounded by phagocytosis‐inhibiting capsules. We took advantage of
the large size of the polysaccharide capsule of the pathogenic yeast Cryptococcus …

Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells

GS Araujo, FL Fonseca, B Pontes, A Torres… - PloS one, 2012 - journals.plos.org
Capsule production is common among bacterial species, but relatively rare in eukaryotic
microorganisms. Members of the fungal Cryptococcus genus are known to produce …

The polysaccharide capsule of the pathogenic fungus Cryptococcus neoformans enlarges by distal growth and is rearranged during budding

O Zaragoza, A Telzak, RA Bryan… - Molecular …, 2006 - Wiley Online Library
The capsule of Cryptococcus neoformans can undergo dramatic enlargement, a
phenomenon associated with virulence. A prior study that used Ab to the capsule as a …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules

S Frases, B Pontes, L Nimrichter… - Proceedings of the …, 2009 - National Acad Sciences
The human pathogenic fungus Cryptococcus neoformans has a distinctive polysaccharide
(PS) capsule that enlarges during infection. The capsule is essential for virulence, but the …