Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts

JC Chen, BA Johnson, DW Erikson… - Human …, 2014 - academic.oup.com
STUDY QUESTION How does seminal plasma (SP) affect the transcriptome of human
primary endometrial epithelial cells (eEC) and stromal fibroblasts (eSF)? SUMMARY …

Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on …

AF George, KS Jang, M Nyegaard… - Human …, 2020 - academic.oup.com
STUDY QUESTION Do seminal plasma (SP) and its constituents affect the decidualization
capacity and transcriptome of human primary endometrial stromal fibroblasts (eSFs) …

[HTML][HTML] Seminal fluid and fertility in women

SA Robertson, DJ Sharkey - Fertility and sterility, 2016 - Elsevier
Seminal fluid is often viewed as simply a vehicle to carry sperm to fertilize the oocyte, but a
more complex function in influencing female reproductive physiology is now evident …

Seminal plasma modulates expression of endometrial inflammatory meditators in the bovine

LA Ibrahim, JA Rizo, PLP Fontes, GC Lamb… - Biology of …, 2019 - academic.oup.com
Seminal plasma has conventionally been viewed as a transport and survival medium for
mammalian sperm; however, its role now extends beyond this process to actively targeting …

Seminal plasma enhances and accelerates progesterone-induced decidualisation of human endometrial stromal cells

U Doyle, N Sampson, C Zenzmaier… - Reproduction …, 2012 - CSIRO Publishing
In preparation for embryo implantation, endometrial stromal cells (ESC) undergo
differentiation, termed decidualisation. Enhancing endometrial decidualisation may …

Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells

DJ Sharkey, AM Macpherson… - Molecular human …, 2007 - academic.oup.com
Exposure to semen elicits an inflammatory response in the female reproductive tract of
rodents and other animals. The nature and regulation of any similar response in humans is …

Seminal fluid and reproduction: much more than previously thought

JJ Bromfield - Journal of assisted reproduction and genetics, 2014 - Springer
The influence of seminal plasma on the cytokine and immune uterine environment is well
characterised in mice and humans, while the effects of disruption to uterine seminal plasma …

[HTML][HTML] The female response to seminal fluid

JE Schjenken, SA Robertson - Physiological Reviews, 2020 - journals.physiology.org
Seminal fluid is often assumed to have just one function in mammalian reproduction,
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …

Role of high molecular weight seminal vesicle proteins in eliciting the uterine inflammatory response to semen in mice

SA Robertson, VJ Mau, KP Tremellen… - …, 1996 - rep.bioscientifica.com
Mating evokes a characteristic pattern of molecular and cellular events in the rodent
reproductive tract, including an infiltration of the endometrial stroma and uterine lumen with …

[HTML][HTML] Seminal fluid-mediated inflammation in physiology and pathology of the female reproductive tract

AO Adefuye, HA Adeola, KJ Sales… - Journal of immunology …, 2016 - hindawi.com
Inflammation is a multifaceted process involving a host of resident and recruited immune
cells that eliminate the insult or injury and initiate tissue repair. In the female reproductive …