[HTML][HTML] Topical use of tranexamic acid in cardiac surgery—a review and meta-analysis of four randomized controlled trials
T Vaněk, Z Straka - Cor et Vasa, 2013 - Elsevier
The article deals with the issue of topical use of tranexamic acid in cardiac surgery. Four
randomized, double-blind trials comparing tranexamic acid vs. placebo were identified in the …
randomized, double-blind trials comparing tranexamic acid vs. placebo were identified in the …
[HTML][HTML] Tranexamic acid in coronary artery surgery: one-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial
Background Tranexamic acid reduces blood loss and transfusion requirements in cardiac
surgery but may increase the risk of coronary graft thrombosis. We previously reported the …
surgery but may increase the risk of coronary graft thrombosis. We previously reported the …
[HTML][HTML] Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial
F Monaco, P Nardelli, L Pasin, G Barucco… - British Journal of …, 2020 - Elsevier
Background Bleeding and transfusions affect mortality in aortic surgery. Although tranexamic
acid significantly reduced bleeding in multiple settings, its role in major vascular surgery was …
acid significantly reduced bleeding in multiple settings, its role in major vascular surgery was …
Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary artery bypass operations: a double-blind, randomized, placebo …
RS Brown, BK Thwaites, PD Mongan - Anesthesia & Analgesia, 1997 - journals.lww.com
We evaluated the effects of tranexamic acid (TA) administered before and after
cardiopulmonary bypass (CPB) in a prospective, randomized, placebo-controlled, double …
cardiopulmonary bypass (CPB) in a prospective, randomized, placebo-controlled, double …
[PDF][PDF] Tranexamic acid
C Earnshaw, M Poole - Anaesth Tut Week, 2019 - anestesiaentrerios.org.ar
Standard dose is 1g intravenously, over a minimum of 10 minutes. The main mechanism of
action is anti-fibrinolytic activity. It also possesses anti-inflammatory effects and may help …
action is anti-fibrinolytic activity. It also possesses anti-inflammatory effects and may help …
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss
K Ker, D Prieto-Merino, I Roberts - Journal of British Surgery, 2013 - academic.oup.com
Background Tranexamic acid (TXA) reduces blood transfusion in surgery but the extent of
the reduction in blood loss and how it relates to the dose of TXA is unclear. Methods A …
the reduction in blood loss and how it relates to the dose of TXA is unclear. Methods A …
Tranexamic acid reduces blood loss in off-pump coronary artery bypass surgery
RJ Taghaddomi, A Mirzaee, AS Attar… - Journal of cardiothoracic …, 2009 - Elsevier
OBJECTIVE: This study was designed to evaluate the hemostatic effect of tranexamic acid in
off-pump coronary artery bypass surgery. DESIGN: A prospective, randomized, double-blind …
off-pump coronary artery bypass surgery. DESIGN: A prospective, randomized, double-blind …
Tranexamic acid reduces perioperative blood loss in adult patients having spinal fusion surgery
J Wong, H El Beheiry, YR Rampersaud… - Anesthesia & …, 2008 - journals.lww.com
BACKGROUND: Spinal reconstructive surgery in adults can be associated with significant
blood loss, often requiring allogeneic blood transfusion. The objective of this randomized …
blood loss, often requiring allogeneic blood transfusion. The objective of this randomized …
Double-blind, randomized controlled trial of tranexamic acid in minor lumbar spine surgery: no effect on operative time, intraoperative blood loss, or complications
S Elmose, MØ Andersen, EB Andresen… - Journal of Neurosurgery …, 2019 - thejns.org
OBJECTIVE The purpose of this study was to investigate the effect of tranexamic acid (TXA)
compared to placebo in low-risk adult patients undergoing elective minor lumbar spine …
compared to placebo in low-risk adult patients undergoing elective minor lumbar spine …
Tranexamic acid is associated with less blood transfusion in off-pump coronary artery bypass graft surgery: a systematic review and meta-analysis
SCA Ma, W Brindle, G Burton, S Gallacher… - Journal of cardiothoracic …, 2011 - Elsevier
OBJECTIVE:: Tranexamic acid reduces blood loss and transfusion in on-pump coronary
artery bypass graft (CABG) surgery. Compared with on-pump, off-pump surgery is …
artery bypass graft (CABG) surgery. Compared with on-pump, off-pump surgery is …