[HTML][HTML] Dietary polyphenols may affect DNA methylation
M Fang, D Chen, CS Yang - The Journal of nutrition, 2007 - Elsevier
Certain dietary polyphenols, such as (−)-epigallocatechin 3-gallate (EGCG) from green tea
and genistein from soybean, have been demonstrated to inhibit DNA methyltransferases …
and genistein from soybean, have been demonstrated to inhibit DNA methyltransferases …
Diet and DNA methylation interactions in cancer prevention
SA Ross - Annals of the New York Academy of Sciences, 2003 - Wiley Online Library
Epigenetic events constitute an important mechanism by which gene function is selectively
activated or inactivated. Since epigenetic events are susceptible to change they offer …
activated or inactivated. Since epigenetic events are susceptible to change they offer …
Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components
Y Li, TO Tollefsbol - Current medicinal chemistry, 2010 - ingentaconnect.com
It is well established that aberrant gene regulation by epigenetic mechanisms can develop
as a result of pathological processes such as cancer. Methylation of CpG islands is an …
as a result of pathological processes such as cancer. Methylation of CpG islands is an …
Tea polyphenol (−)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines
MZ Fang, Y Wang, N Ai, Z Hou, Y Sun, H Lu, W Welsh… - Cancer research, 2003 - AACR
Hypermethylation of CpG islands in the promoter regions is an important mechanism to
silence the expression of many important genes in cancer. The hypermethylation status is …
silence the expression of many important genes in cancer. The hypermethylation status is …
[HTML][HTML] Assessing the effects of high methionine intake on DNA methylation
RA Waterland - The Journal of nutrition, 2006 - Elsevier
Methylation of DNA occurs at cytosines within CpG (cytosine-guanine) dinucleotides and is
1 of several epigenetic mechanisms that serve to establish and maintain tissue-specific …
1 of several epigenetic mechanisms that serve to establish and maintain tissue-specific …
Epigenetic modifications and human pathologies: cancer and CVD
SJ Duthie - Proceedings of the Nutrition Society, 2011 - cambridge.org
Epigenetic changes are inherited alterations in DNA that affect gene expression and
function without altering the DNA sequence. DNA methylation is one epigenetic process …
function without altering the DNA sequence. DNA methylation is one epigenetic process …
[HTML][HTML] Phytochemicals in cancer prevention: modulating epigenetic alterations of DNA methylation
S Pop, AM Enciu, I Tarcomnicu, E Gille… - Phytochemistry Reviews, 2019 - Springer
Cancer can take many years to develop from initiation to progression. The long period of
development might represent an opportunity to use multi-functional, multi-targeted …
development might represent an opportunity to use multi-functional, multi-targeted …
DNA methylation, cancer susceptibility, and nutrient interactions
CD Davis, EO Uthus - Experimental biology and medicine, 2004 - journals.sagepub.com
DNA methylation is an important epigenetic mechanism of transcriptional control. DNA
methylation plays an essential role in maintaining cellular function, and changes in …
methylation plays an essential role in maintaining cellular function, and changes in …
[HTML][HTML] The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction
LA Poirier - The Journal of nutrition, 2002 - Elsevier
In the early 1930s, the group of Banting and Best showed that the choline moiety of lecithin
was responsible for the prevention of the fatty livers produced in pancreatectomized dogs …
was responsible for the prevention of the fatty livers produced in pancreatectomized dogs …
Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy
MZ Fang, D Chen, Y Sun, Z Jin, JK Christman… - Clinical Cancer …, 2005 - AACR
Purpose: We have previously shown the reactivation of some methylation-silenced genes in
cancer cells by (−)-epigallocatechin-3-gallate, the major polyphenol from green tea. To …
cancer cells by (−)-epigallocatechin-3-gallate, the major polyphenol from green tea. To …
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