Imbalance between Th17 cells and regulatory T cells during monophasic experimental autoimmune uveitis

L Zhang, F Wan, J Song, K Tang, F Zheng, J Guo… - Inflammation, 2016 - Springer
The aim of this study is to explore the dynamic changes in IL-17-expressing T cells
(Th17)/Treg expression in monophasic experimental autoimmune uveitis (mEAU). mEAU …

Differential roles for IFN-γ and IL-17 in experimental autoimmune uveoretinitis

T Yoshimura, KH Sonoda, Y Miyazaki… - International …, 2008 - academic.oup.com
Abstract IL-17-producing CD4+ T cells, so called Th17 cells, constitute a newly identified
inflammatogenic cell population, which is critically involved in some inflammatory diseases …

Regulation of antigen specific Th17 cells differentiation in experimental autoimmune uveitis

HT Chen, H Wang, M Zhao, B Hou - … yan ke za Zhi] Chinese Journal …, 2012 - europepmc.org
Objective To assess the regulation of antigen specific Th17 cells differentiation in
experimental autoimmune uveitis (EAU). Methods A randomized controlled trials research …

Dysregulated Th17/Treg cell axis is correlated with local and systemic immune response in human intermediate uveitis

C Saini, L Sapra, P Puri, PK Mishra, R Chawla… - Immunology …, 2024 - Elsevier
Th17/Treg cell balance is essential for immune homeostasis and when disrupted, is
associated with the occurrence and development of inflammation in numerous autoimmune …

Blockade of interleukin-6 signaling suppresses not only Th17 but also interphotoreceptor retinoid binding protein–specific Th1 by promoting regulatory T cells in …

H Haruta, N Ohguro, M Fujimoto… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: Both Th17 and Th1 cells contribute to experimental autoimmune uveoretinitis
(EAU). Interleukin-6 (IL-6) blockade inhibits Th17 differentiation in EAU and potently …

[HTML][HTML] Coordinated gene expression of Th17-and Treg-associated molecules correlated with resolution of the monophasic experimental autoimmune uveitis

X Jia, M Hu, C Wang, C Wang, F Zhang, Q Han… - Molecular …, 2011 - ncbi.nlm.nih.gov
Purpose To investigate the role of T-cell-mediated immune response in a monophasic
experimental autoimmune uveitis (EAU). Methods A monophasic EAU was induced in Lewis …

Imbalance of Th17/Treg cells in pathogenesis of patients with human leukocyte antigen B27 associated acute anterior uveitis

Z Zhuang, Y Wang, G Zhu, Y Gu, L Mao, M Hong, Y Li… - Scientific reports, 2017 - nature.com
Th17 and regulatory T cells, involved in the pathogenesis of several autoimmune diseases,
are new lineages of CD4+ T helper cells. However, the role of their imbalance in human …

Functionally distinct IFN‐γ+IL‐17A+ Th cells in experimental autoimmune uveitis: T‐cell heterogeneity, migration, and steroid response

YH Chen, M Eskandarpour, A Gondrand… - European Journal of …, 2020 - Wiley Online Library
Immunopathogenic roles for both Th1 (CD4+ IFN‐γ+) and Th17 (CD4+ IL‐17A+) cells have
been demonstrated in experimental autoimmune uveitis (EAU). However, the role for …

Regulatory T cells and IL-17A levels in noninfectious uveitis

MCE Guedes, MJ Arroz, C Martins… - Graefe's Archive for …, 2020 - Springer
Abstract Purpose Regulatory T cells (Tregs) have been intensively studied in a myriad of
autoimmune diseases. As for noninfectious uveitis (NIU), results have been contradictory …

Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis

T Yoshimura, KH Sonoda, N Ohguro, Y Ohsugi… - …, 2009 - academic.oup.com
Objectives. Human endogenous uveitis is one of the sight-threatening diseases associated
with variety of systemic disorders, such as Behcet's disease and sarcoidosis. Recently …