DNA methylation patterns in human tripronucleate zygotes
Y Xu, JJ Zhang, JA Grifo, LC Krey - Molecular human …, 2004 - academic.oup.com
In mammals, the dynamic reprogramming of DNA methylation begins during gametogenesis
and continues through embryogenesis. Recently, immunofluorescence staining with an …
and continues through embryogenesis. Recently, immunofluorescence staining with an …
Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development
MC Golding, GL Williamson, TK Stroud… - Molecular …, 2011 - Wiley Online Library
In studies of somatic cell nuclear transfer (SCNT), the ability of factors within the oocyte to
epigenetically reprogram transferred nuclei is essential for embryonic development of the …
epigenetically reprogram transferred nuclei is essential for embryonic development of the …
DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos
I Stancheva, O El-Maarri, J Walter, A Niveleau… - Developmental …, 2002 - Elsevier
The levels of genomic DNA methylation in vertebrate species display a wide range of
developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the …
developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the …
Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development
The prenatal period of germ cell development is a key time of epigenetic programming in the
male, a window of development that has been shown to be influenced by maternal factors …
male, a window of development that has been shown to be influenced by maternal factors …
Global changes in genomic methylation levels during early development of the zebrafish embryo
AA Mhanni, RA McGowan - Development genes and evolution, 2004 - Springer
We have examined the methylation status of the zebrafish genome during early
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …
DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes
Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …
Aberrant DNA methylation imprints in aborted bovine clones
JH Liu, S Yin, B Xiong, Y Hou… - Molecular …, 2008 - Wiley Online Library
Genomic imprinting plays a very important role during development and its abnormality may
heavily undermine the developmental potential of bovine embryos. Because of limited …
heavily undermine the developmental potential of bovine embryos. Because of limited …
Methylation dynamics of imprinted genes in mouse germ cells
D Lucifero, C Mertineit, HJ Clarke, TH Bestor… - Genomics, 2002 - Elsevier
DNA methylation differences between maternal and paternal alleles of many imprinted
genes are inherited from the male and female gametes and subsequently maintained during …
genes are inherited from the male and female gametes and subsequently maintained during …
Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos
F Santos, V Zakhartchenko, M Stojkovic, A Peters… - Current Biology, 2003 - cell.com
During differentiation, somatic nuclei acquire highly specialized DNA and chromatin
modifications, which are thought to result in cellular memory of the differentiated state [1] …
modifications, which are thought to result in cellular memory of the differentiated state [1] …
[HTML][HTML] Limited demethylation leaves mosaic‐type methylation states in cloned bovine pre‐implantation embryos
YK Kang, JS Park, DB Koo, YH Choi, SU Kim… - The EMBO …, 2002 - embopress.org
Cloning by nuclear transfer (NT) has been riddled with difficulties: most clones die before
birth and survivors frequently display growth abnormalities. The cross‐species similarity in …
birth and survivors frequently display growth abnormalities. The cross‐species similarity in …