DNA methylation patterns in human tripronucleate zygotes

Y Xu, JJ Zhang, JA Grifo, LC Krey - Molecular human …, 2004 - academic.oup.com
In mammals, the dynamic reprogramming of DNA methylation begins during gametogenesis
and continues through embryogenesis. Recently, immunofluorescence staining with an …

Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development

MC Golding, GL Williamson, TK Stroud… - Molecular …, 2011 - Wiley Online Library
In studies of somatic cell nuclear transfer (SCNT), the ability of factors within the oocyte to
epigenetically reprogram transferred nuclei is essential for embryonic development of the …

DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos

I Stancheva, O El-Maarri, J Walter, A Niveleau… - Developmental …, 2002 - Elsevier
The levels of genomic DNA methylation in vertebrate species display a wide range of
developmental dynamics. Here, we show that in contrast to mice, the paternal genome of the …

Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development

KM Niles, D Chan, S La Salle, CC Oakes, JM Trasler - PLoS One, 2011 - journals.plos.org
The prenatal period of germ cell development is a key time of epigenetic programming in the
male, a window of development that has been shown to be influenced by maternal factors …

Global changes in genomic methylation levels during early development of the zebrafish embryo

AA Mhanni, RA McGowan - Development genes and evolution, 2004 - Springer
We have examined the methylation status of the zebrafish genome during early
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …

DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes

E Ivanova, S Canovas, S Garcia-Martínez, R Romar… - Clinical …, 2020 - Springer
Preimplantation embryos experience profound resetting of epigenetic information inherited
from the gametes. Genome-wide analysis at single-base resolution has shown similarities …

Aberrant DNA methylation imprints in aborted bovine clones

JH Liu, S Yin, B Xiong, Y Hou… - Molecular …, 2008 - Wiley Online Library
Genomic imprinting plays a very important role during development and its abnormality may
heavily undermine the developmental potential of bovine embryos. Because of limited …

Methylation dynamics of imprinted genes in mouse germ cells

D Lucifero, C Mertineit, HJ Clarke, TH Bestor… - Genomics, 2002 - Elsevier
DNA methylation differences between maternal and paternal alleles of many imprinted
genes are inherited from the male and female gametes and subsequently maintained during …

Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos

F Santos, V Zakhartchenko, M Stojkovic, A Peters… - Current Biology, 2003 - cell.com
During differentiation, somatic nuclei acquire highly specialized DNA and chromatin
modifications, which are thought to result in cellular memory of the differentiated state [1] …

[HTML][HTML] Limited demethylation leaves mosaic‐type methylation states in cloned bovine pre‐implantation embryos

YK Kang, JS Park, DB Koo, YH Choi, SU Kim… - The EMBO …, 2002 - embopress.org
Cloning by nuclear transfer (NT) has been riddled with difficulties: most clones die before
birth and survivors frequently display growth abnormalities. The cross‐species similarity in …