The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Elucidating the Immunological Function of the Cryptococcus Neoformans Capsule

A Vecchiarelli, E Pericolini, E Gabrielli… - Future …, 2013 - Taylor & Francis
The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent
of life-threatening infections in immunocompromised subjects. A unique characteristic of …

The capsular dynamics of Cryptococcus neoformans

D McFadden, O Zaragoza, A Casadevall - TRENDS in Microbiology, 2006 - cell.com
Cryptococcus neoformans is a soil-dwelling fungus that causes life-threatening illness in
immunocompromised individuals and latently infects many healthy individuals. C …

[PDF][PDF] Dismantling the Cryptococcus coat

CA D'Souza, J Heitman - Trends in microbiology, 2001 - Citeseer
Cryptococcus neoformans is an encapsulated yeast and an opportunistic fungal pathogen
responsible for lifethreatening infections of the central nervous system (CNS) in HIV-1 …

Toward an Integrated Model of Capsule Regulation in Cryptococcus neoformans

BC Haynes, ML Skowyra, SJ Spencer, SR Gish… - PLoS …, 2011 - journals.plos.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes serious human
disease in immunocompromised populations. Its polysaccharide capsule is a key virulence …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Virulence mechanisms and Cryptococcus neoformans pathogenesis

JA Alspaugh - Fungal Genetics and Biology, 2015 - Elsevier
The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …

How Sweet it is! Cell Wall Biogenesis and Polysaccharide Capsule Formation in Cryptococcus neoformans

TL Doering - Annual review of microbiology, 2009 - annualreviews.org
Cryptococcus neoformans is a pathogenic fungus responsible for severe opportunistic
infections. The most prominent feature of this yeast is its elaborate polysaccharide capsule …

Cell wall α‐1,3‐glucan is required to anchor the Cryptococcus neoformans capsule

AJ Reese, TL Doering - Molecular microbiology, 2003 - Wiley Online Library
Cryptococcus neoformans is an opportunistic pathogen responsible for serious disease in
humans. Critical for virulence of this fungus is an elaborate polysaccharide capsule, which …