Opioid overdose is the leading cause of death for Americans 25 to 64 years of age, and
opioid use disorder affects> 2 million Americans. The epidemiology of opioid-associated out …

Objectives: To investigate clinical outcomes in a cohort of opioid overdose patients treated in
an out‐of‐hospital urban setting noted for a high prevalence of IV opioid use. Methods: A …

Objective: To determine whether naloxone administered IV to out‐of‐hospital patients with
suspected opioid overdose would have a more rapid therapeutic onset than naloxone given …

Opioids are the most potent of all analgesics. Although traditionally used solely for acute self-
limited conditions and palliation of severe cancer-associated pain, a movement to promote …

Background: Opioid overdoses are at epidemic levels in the United States. Emergency
Medical Service (EMS) providers may administer naloxone to restore patient breathing and …

Rationale: Opioid abuse is increasing, but its impact on critical care resources in the United
States is unknown. Objectives: We hypothesized that there would be a rising need for critical …

Alexander Y. Walley, MD, MSc OPIOID OVERDOSE IS A BURGEONING PUBLIC HEALTH
crisis, accounting for at least 16 000 deaths annu-ally in the United States. 1 Opioid …

Consider “Jane,” a 30-year-old female patient brought in by emergency medical services
(EMS) to the emergency department (ED), reflecting just one of more than 100,000 opioid …

Opioid overdose and mortality have increased at an alarming rate prompting new public
health initiatives to reduce drug poisoning. One initiative is to expand access to the opioid …

Study objective We aim to determine whether administration of higher doses of naloxone for
the treatment of opioid overdose is associated with increased pulmonary complications …