Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression
Background The neuropeptide oxytocin regulates mammalian social behavior. Disruptions
in oxytocin signaling are a feature of many psychopathologies. One commonly studied …
in oxytocin signaling are a feature of many psychopathologies. One commonly studied …
Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience
Genetic approaches have improved our understanding of the neurobiological basis of social
behavior and cognition. For instance, common polymorphisms of genes involved in oxytocin …
behavior and cognition. For instance, common polymorphisms of genes involved in oxytocin …
Brain region-specific methylation in the promoter of the murine oxytocin receptor gene is involved in its expression regulation
H Harony-Nicolas, S Mamrut, L Brodsky… - …, 2014 - Elsevier
Oxytocin is a nine amino acid neuropeptide that is known to play a critical role in fetal
expulsion and breast-feeding, and has been recently implicated in mammalian social …
expulsion and breast-feeding, and has been recently implicated in mammalian social …
[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
An epigenetic rheostat of experience: DNA methylation of OXTR as a mechanism of early life allostasis
Oxytocin is a neuropeptide hormone which is involved in regulation of social behavior,
stress response, muscle contraction, and metabolism. Oxytocin signaling is dependent on its …
stress response, muscle contraction, and metabolism. Oxytocin signaling is dependent on its …
Epigenetic evidence for involvement of the oxytocin receptor gene in obsessive–compulsive disorder
Background Obsessive–compulsive disorder (OCD) is a chronic neurodevelopmental
disorder that affects up to 3% of the general population. Although epigenetic mechanisms …
disorder that affects up to 3% of the general population. Although epigenetic mechanisms …
Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain
In humans, the neuropeptide oxytocin plays a critical role in social and emotional behavior.
The actions of this molecule are dependent on a protein that acts as its receptor, which is …
The actions of this molecule are dependent on a protein that acts as its receptor, which is …
Oxytocin receptor expression patterns in the human brain across development
Oxytocin plays a vital role in social behavior and homeostatic processes, with animal models
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …
Associations between oxytocin receptor gene (OXTR) methylation, plasma oxytocin, and attachment across adulthood
The neuropeptide oxytocin (OT) has been implicated in a wide range of affiliative processes.
OT exerts its functions via OT receptors, which are encoded by the oxytocin receptor gene …
OT exerts its functions via OT receptors, which are encoded by the oxytocin receptor gene …
[HTML][HTML] Early nurture epigenetically tunes the oxytocin receptor
AM Perkeybile, CS Carter, KL Wroblewski… - …, 2019 - Elsevier
Mammalian sociality is regulated in part by the neuropeptide oxytocin. In prairie voles, subtle
variation in early life experience changes oxytocin receptor-mediated social behaviors. We …
variation in early life experience changes oxytocin receptor-mediated social behaviors. We …