We performed a stage-by-stage study of DNA methylation patterns in metaphase
chromosomes from blastomeres of triploid and abnormal diploid human embryos. QFH …

DNA methylation level and pattern of human metaphase chromosomes from extraembryonic
tissues (chorionic villi and placental fibroblasts) were analysed in situ. The DNA methylation …

DNA methylation patterns were evaluated during preimplantation mouse development by
analyzing the binding of monoclonal antibody to 5-methylcytosine (5-MeC) on metaphase …

Methylation pattern peculiarities revealed by immunocytochemical analysis of metaphase
chromosomes from preimplanted human embryos with monoclonal antibodies against 5 …

We report on observations of the global methylation/demethylation pattern of both pronuclei
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …

The methylation status of three highly repeated sequences was studied in sperm, eggs and
preimplantation embryos with different combinations of parental chromosomes. High levels …

Studies on both pure isolated derivatives and mixed tissues have shown that trophectoderm
and prim~'ve endoderm lineages of the mouse exhibit cell-lineage-sl~ zmfic patterns of DNA …

REPRODUCTION Page 1 REPRODUCTION RESEARCH Chromosome
hydroxymethylation patterns in human zygotes and cleavage-stage embryos Olga A …

Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …

The fertilized mouse egg actively demethylates the paternal genome within a few hours after
fertilization, whereas the maternal genome is only passively demethylated by a replication …