Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals

A Henckel, K Nakabayashi, LA Sanz… - Human molecular …, 2009 - academic.oup.com
Mono-allelic expression of imprinted genes from either the paternal or the maternal allele is
mediated by imprinting control regions (ICRs), which are epigenetically marked in an allele …

Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive

S Maupetit-Méhouas, B Montibus, D Nury… - Nucleic acids …, 2016 - academic.oup.com
Parental allele-specific expression of imprinted genes is mediated by imprinting control
regions (ICRs) that are constitutively marked by DNA methylation imprints on the maternal or …

Sexual dimorphism in parental imprint ontogeny and contribution to embryonic development

D Bourc'his, C Proudhon - Molecular and cellular endocrinology, 2008 - Elsevier
Genomic imprinting refers to the functional non-equivalence of parental genomes in
mammals that results from the parent-of-origin allelic expression of a subset of genes …

De novo DNA methylation through the 5′-segment of the H19 ICR maintains its imprint during early embryogenesis

H Matsuzaki, E Okamura, T Takahashi… - …, 2015 - journals.biologists.com
Genomic imprinting is a major monoallelic gene expression regulatory mechanism in
mammals, and depends on gamete-specific DNA methylation of specialized cis-regulatory …

DNA methylation dynamics of genomic imprinting in mouse development

JM SanMiguel, MS Bartolomei - Biology of reproduction, 2018 - academic.oup.com
DNA methylation is an essential epigenetic mark crucial for normal mammalian
development. This modification controls the expression of a unique class of genes …

Imprinting mechanisms

M Constância, B Pickard, G Kelsey, W Reik - Genome research, 1998 - genome.cshlp.org
A number of recent studies have provided new insights into mechanisms that regulate
genomic imprinting in the mammalian genome. Regions of allele-specific differential …

Domain-specific response of imprinted genes to reduced DNMT1

JR Weaver, G Sarkisian, C Krapp, J Mager… - … and cellular biology, 2010 - Taylor & Francis
Imprinted genes are expressed in a monoallelic, parent-of-origin-specific manner. Clusters
of imprinted genes are regulated by imprinting control regions (ICRs) characterized by DNA …

Developmental regulation of somatic imprints

RM John, L Lefebvre - Differentiation, 2011 - Elsevier
Genomic imprinting is an epigenetic phenomenon guiding the allele-specific marking of
parental alleles. Genes regulated by imprinting are only or preferentially expressed from a …

[HTML][HTML] Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue

K Woodfine, JE Huddleston, A Murrell - Epigenetics & chromatin, 2011 - Springer
Background Genes subject to genomic imprinting are mono-allelically expressed in a parent-
of-origin dependent manner. Each imprinted locus has at least one differentially methylated …

Chromatin mechanisms in genomic imprinting

S Kacem, R Feil - Mammalian genome, 2009 - Springer
Mammalian imprinted genes are clustered in chromosomal domains. Their mono-allelic,
parent-of-origin-specific expression is regulated by imprinting control regions (ICRs), which …