SUMO is a novel ubiquitin-like protein that can covalently modify a large number of nuclear
proteins. SUMO modification has emerged as an important regulatory mechanism for protein …

Small ubiquitin-like modifiers (SUMO) conjugation to cellular proteins is a reversible
posttranslational modification that mediates the protein's function, subcellular localization …

SUMOylation has been shown to modulate DNA replication/repair, cell cycle progression,
signal transduction, and the hypoxic response. SUMO (small ubiquitin-like modifier)-specific …

Sentrin/SUMO (small ubiquitin-like modifier)-specific proteases (SENPs) have been
implicated in the development of prostate cancer. However, due to the low abundance of …

SUMOylation is a reversible process regulated by a family of sentrin/SUMO-specific
proteases (SENPs). Of the six SENP family members, except for SENP1 and SENP2, the …

Abstract SUMO-specific protease 1 (SENP1) is a member of de-SUMOylation protease
family and has an important role in the regulation of androgen receptor-dependent …

The acceptor sites for small ubiquitin-like modifier (SUMO) are conserved in the N-terminal
domains of several nuclear receptors. Here, we show that androgens induce rapid and …

Posttranslational modification by small ubiquitin-like modifier (SUMO) controls diverse
cellular processes including transcriptional regulation, nuclear transport, cell-cycle …

SUMO conjugation emerges as an important mechanism in regulating protein localization,
stability and activity. SUMOylation is a dynamic process and can be reversed by a family of …

SUMO (also called Sentrin) is a ubiquitin-like protein that plays an important role in
regulating protein function and localization. It is known that several nuclear receptors are …