DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …

DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …

Background DNA methylation is an epigenetic modification that is studied at a single-base
resolution with bisulfite treatment followed by high-throughput sequencing. After alignment …

Aims: To compare the performance of four sequence-based and one microarray methods for
DNA methylation profiling. Methods: DNA from two cell lines were profiled by reduced …

As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

DNA cytosine methylation is a central epigenetic modification which plays critical roles in
cellular processes including genome regulation, development and disease. Here, we review …

DNA methylation is an epigenetic mark linking DNA sequence and transcription regulation,
and therefore plays an important role in phenotypic plasticity. The ideal whole genome …

DNA methylation is an indispensible epigenetic modification required for regulating the
expression of mammalian genomes. Immunoprecipitation-based methods for DNA …

DNA methylation is an important component of epigenetic modifications that influences the
transcriptional machinery and is aberrant in many human diseases. Several methods have …