Melatonin, an indole formed enzymatically from L-tryptophan, is the most versatile and
ubiquitous hormone molecule produced not only in all animals but also in some plants. This …

Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal
gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of …

Introduction: Melatonin is a pineal hormone that has acquired several unique modes of
regulating the physiological effects in mammals due to its characteristic phylogenetic history …

Melatonin, a molecule with antioxidant properties that is widely distributed in the animal
kingdom, has now been shown to exist in the plant kingdom, including edible plants. Our …

This review summarizes the present knowledge on melatonin in several areas on
physiology and discusses various prospects of its clinical utilization. Ever increasing …

Twenty-four edible plants were investigated for the presence of melatonin, heretofore
considered to be a molecule found only in the animal kingdom. The amount of melatonin in …

Melatonin was thought to originate primarily from the pineal gland and to be secreted during
the night, but recent studies revealed that gastrointestinal (GI) tract presents another, many …

Preservation of a robust circadian rhythmicity (particulsarly of the sleep/wake cycle), a
proper nutrition and adequate physical exercise are key elements for healthy aging. Aging …

Melatonin (MEL) has been revealed as a phylogenetically conserved molecule with a
ubiquitous distribution from primitive photosynthetic bacteria to higher plants, including …

Study Objectives: Melatonin is an important neurohormone, which mediates circadian
rhythms and the sleep cycle. As such, it is a popular and readily available supplement for the …