Phenotypic characteristics are known to vary substantially among different ethnicities around
the globe. These variations are mediated by number of stochastic events and cannot be …

Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …

DNA methylation patterns are important for establishing cell, tissue, and organism
phenotypes, but little is known about their contribution to natural human variation. To …

Genomic DNA methylation profiles exhibit substantial variation within the human population,
with important functional implications for gene regulation. So far little is known about the …

Background Ethnic differences in human DNA methylation have been shown for a number of
CpG sites, but the genome-wide patterns and extent of these differences are largely …

Multiple recent studies highlight that genetic variants can have strong impacts on a
significant proportion of the human DNA methylome. Methylation quantitative trait loci, or …

Background DNA methylation is associated with non-communicable diseases (NCDs) and
related traits. Methylation data on continental African ancestries are currently scarce, even …

Background The predominant model for regulation of gene expression through DNA
methylation is an inverse association in which increased methylation results in decreased …

Purpose: Aging is one of the most important risk factors for a number of human diseases.
Epigenetic alterations, including changes in DNA methylation patterns, have been reported …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …