Dear Editor, Epiboly, the thinning and spreading of blastoderm over the yolk cells, is the first
morphogenetic movement in zebrafish. Studies of zebrafish epiboly have provided insights …

Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation.
Despite of its fundamental function, little is known about the molecular mechanisms that …

Histone lysine methylation is important in early zebrafish development; however, the role of
histone arginine methylation in this process remains unclear. H3R2me2a, generated by …

Protein arginine methyltransferase (PRMT) 1 is the most conserved and widely distributed
PRMT in eukaryotes. PRMT8 is a vertebrate-restricted paralogue of PRMT1 with an extra N …

ABSTRACT Protein arginine methyltransferase 5 (Prmt5), a type II arginine
methyltransferase, symmetrically dimethylates arginine in nuclear and cytoplasmic proteins …

Background Asymmetric arginine dimethylation of histone H4R3 to H4R3me2a by protein
arginine methyltransferase 1 (PRMT1) has been implicated to play a key role in gene …

Protein arginine methyltransferase (PRMT) 1 is the predominant type I methyltransferase in
mammals. In the present study, we used zebrafish (Danio rerio) as the model system to …

The homeobox transcription factor Mtx2 is essential for epiboly, the first morphogenetic
movement of gastrulation in zebrafish. Morpholino knockdown of Mtx2 results in stalling of …

Histone arginine methylation has emerged as an important histone modification involved in
gene regulation. Protein arginine methyltransferase (PRMT) 4 and 5 have been shown to …

In zebrafish, BMP signaling establishes cell identity along the dorsoventral (DV) axis during
gastrulation. Owing to the early requirements of BMP activity in DV patterning, it has been …