Atherosclerosis depends on risk factors such as hyperlipidemia, smoking, hypertension and
diabetes. Although these risk factors are relatively constant throughout the arterial …

Atherosclerosis is a chronic inflammatory disease that originates at regions of arteries
exposed to disturbances in fluid flow and results in progressive plaque formation in those …

Forces that are associated with blood flow are major determinants of vascular
morphogenesis and physiology. Blood flow is crucial for blood vessel development during …

Abstract Purpose of Review This review aims to summarize the latest findings on
mechanosensing in atherosclerosis, elucidating the molecular mechanisms, cellular players …

Haemodynamic factors influence all forms of vascular growth (vasculogenesis,
angiogenesis, arteriogenesis). Because of its prominent role in atherosclerosis, shear stress …

Atherosclerosis is a focal disease that develops preferentially where nonlaminar, disturbed
blood flow occurs, such as branches, bifurcations, and curvatures of large arteries …

Cardiovascular disease (CVD) is a serious health challenge, causing more deaths
worldwide than cancer. The vascular endothelium, which forms the inner lining of blood …

Endothelium health is essential to the regulation of physiological vascular functions.
Because of the critical capability of endothelial cells (ECs) to sense and transduce chemical …

Mechanical stress from blood flow has a significant effect on endothelial physiology, with a
key role in initiating vasoregulatory signals. Disturbances in blood flow, such as in regions of …

Vascular endothelial cells (ECs) play significant roles in regulating circulatory functions.
Mechanical stimuli, including the stretch and shear stress resulting from circulatory pressure …