Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy
LP Gunawardhana, KJ Baines, J Mattes… - Pediatric …, 2014 - Wiley Online Library
Background Asthma is a complex disease that involves both genetic factors and
environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may …
environmental exposures. Aberrant epigenetic modifications, such as DNA methylation, may …
DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma
KM Magnaye, SM Clay… - Proceedings of the …, 2022 - National Acad Sciences
Maternal asthma (MA) is among the most consistent risk factors for asthma in children.
Possible mechanisms for this observation are epigenetic modifications in utero that have …
Possible mechanisms for this observation are epigenetic modifications in utero that have …
[HTML][HTML] Epigenome-wide meta-analysis of DNA methylation and childhood asthma
Background Epigenetic mechanisms, including methylation, can contribute to childhood
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease …
Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation
Background Smoking while pregnant is associated with a myriad of negative health
outcomes in the child. Some of the detrimental effects may be due to epigenetic …
outcomes in the child. Some of the detrimental effects may be due to epigenetic …
DNA methylation in childhood asthma: an epigenome-wide meta-analysis
CJ Xu, C Söderhäll, M Bustamante, N Baïz… - The lancet Respiratory …, 2018 - thelancet.com
Background DNA methylation profiles associated with childhood asthma might provide
novel insights into disease pathogenesis. We did an epigenome-wide association study to …
novel insights into disease pathogenesis. We did an epigenome-wide association study to …
DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study
Background Epigenetic mechanisms could alter the airway epithelial barrier and ultimately
lead to atopic diseases such as asthma. We aimed to identify DNA methylation profiles that …
lead to atopic diseases such as asthma. We aimed to identify DNA methylation profiles that …
Differentially methylated DNA regions in early childhood wheezing: An epigenome‐wide study using saliva
M Popovic, V Fiano, F Fasanelli… - Pediatric Allergy and …, 2019 - Wiley Online Library
Background Epigenetics may play a role in wheezing and asthma development. We aimed
to examine infant saliva DNA methylation in association with early childhood wheezing …
to examine infant saliva DNA methylation in association with early childhood wheezing …
Nasal DNA methylation is associated with childhood asthma
X Zhang, JM Biagini Myers, JD Burleson, A Ulm… - …, 2018 - Taylor & Francis
Aim: We aim to study DNA methylation (DNAm) variations associated with childhood
asthma. Methods: Nasal DNAm was compared between sibling pairs discordant for asthma …
asthma. Methods: Nasal DNAm was compared between sibling pairs discordant for asthma …
Sex‐specific associations of asthma acquisition with changes in DNA methylation during adolescence
Background Underlying biological mechanisms involved in sex differences in asthma status
changes from pre‐to post‐adolescence are unclear. DNA methylation (DNAm) has been …
changes from pre‐to post‐adolescence are unclear. DNA methylation (DNAm) has been …
In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children
AM Neophytou, SS Oh, D Hu, S Huntsman… - Environmental …, 2019 - journals.lww.com
Background: Maternal smoking during pregnancy is a risk factor for chronic disease later in
life and has been associated with variability of DNA methylation at specific cytosine …
life and has been associated with variability of DNA methylation at specific cytosine …
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