DNA methylation is an important epigenetic modification and is frequently altered in cancer.
Convert of 5-methylcytosine (5 mC) to 5-hydroxymethylcytosine (5 hmC) by ten-eleven …

Mammalian DNA is epigenetically marked by 5′-cytosine methylation (5-methylcytosine [5-
mC]). The Ten-eleven translocation (TET) enzymes (TET1, TET2, and TET3) are implicated …

DNA methylation at the 5 position of cytosine (5-mC) is a key epigenetic mark that is
involved in various biological and pathological processes. 5-mC can be converted to 5 …

Dysregulated DNA methylation followed by abnormal gene expression is an epigenetic
hallmark in cancer. DNA methylation is catalyzed by DNA methyltransferases, and the …

DNA methylation at the 5 position of cytosine (5-mC) has emerged as a key epigenetic
marker that plays essential roles in various biological and pathological processes. 5-mC can …

Purpose Methylation of 5th residue of cytosine in CpG island forms 5-methylcytosine which
is stable, heritable epigenetic mark. Methylation levels are broadly governed by …

The TET (ten–eleven translocation) family of α-ketoglutarate (α-KG)-dependent
dioxygenases catalyzes the sequential oxidation of 5-methylcytosine (5mC) to 5 …

Methylation of the fifth position of cytosine (5mC) is an important epigenetic modification of
DNA. It has been shown that the oxidized derivatives of 5mC, namely 5 …

Ten-eleven translocation (TET) enzymes catalyze the oxidation of 5-methylcytosine (5-mC)
to 5-hydroxymethylcytosine (5-hmC) and then to 5-formylcytosine (5-fC) and 5 …

Background Ten-eleven translocation 1 (TET1) is a dioxygenase that converts 5-
methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) to induce DNA demethylation …