Vitamin D receptor activation reduces angiotensin-II–induced dissecting abdominal aortic aneurysm in apolipoprotein E–knockout mice
S Martorell, L Hueso, H Gonzalez-Navarro… - … and Vascular Biology, 2016 - Am Heart Assoc
Objective—Abdominal aortic aneurysm (AAA) is a vascular disorder characterized by
chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with …
chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with …
Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse …
V Nsengiyumva, SM Krishna, CS Moran… - Clinical …, 2020 - portlandpress.com
Vitamin D deficiency has been associated with human abdominal aortic aneurysm (AAA);
however, its role in AAA pathogenesis is unclear. The aim of the present study was to …
however, its role in AAA pathogenesis is unclear. The aim of the present study was to …
Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II–infused apolipoprotein E–deficient mice
D Gavrila, WG Li, ML McCormick… - … , and vascular biology, 2005 - Am Heart Assoc
Background—Abdominal aortic aneurysms (AAAs) in humans are associated with locally
increased oxidative stress and activity of NADPH oxidase. We investigated the hypothesis …
increased oxidative stress and activity of NADPH oxidase. We investigated the hypothesis …
Impaired vitamin D signaling in endothelial cell leads to an enhanced leukocyte-endothelium interplay: implications for atherosclerosis development
M Bozic, Á Álvarez, C de Pablo, MD Sanchez-Niño… - PLoS …, 2015 - journals.plos.org
Endothelial cell activation leading to leukocyte recruitment and adhesion plays an essential
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective …
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective …
β-Carotene Attenuates Angiotensin II-Induced Aortic Aneurysm by Alleviating Macrophage Recruitment in Apoe−/− Mice
K Gopal, P Nagarajan, J Jedy, AT Raj, SK Gnanaselvi… - Plos one, 2013 - journals.plos.org
Abdominal aortic aneurysm (AAA) is a common chronic degenerative disease characterized
by progressive aortic dilation and rupture. The mechanisms underlying the role of α …
by progressive aortic dilation and rupture. The mechanisms underlying the role of α …
Depletion of CD11c+ dendritic cells in apolipoprotein E-deficient mice limits angiotensin II-induced abdominal aortic aneurysm formation and growth
SM Krishna, CS Moran, RJ Jose, S Lazzaroni… - Clinical …, 2019 - portlandpress.com
Objective: The role of chronic inflammation in abdominal aortic aneurysm (AAA) is
controversial. CD11c+ antigen-presenting cells (APCs)(dendritic cells (DCs)) have been …
controversial. CD11c+ antigen-presenting cells (APCs)(dendritic cells (DCs)) have been …
PPARδ reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice by regulating extracellular matrix homeostasis and …
JS Hwang, HJ Kim, G Kim, ES Kang, SA Ham… - International journal of …, 2014 - Elsevier
Background Abdominal aortic aneurysm (AAA) is an inflammatory disorder characterized by
a localized degradation of connective tissue and apoptosis of vascular smooth muscle cells …
a localized degradation of connective tissue and apoptosis of vascular smooth muscle cells …
Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation
Y Ding, X Li, M Zhou, L Cai, H Tang, T Xie, Z Shi… - Vascular …, 2021 - Elsevier
Objective Rivaroxaban is a specific factor Xa (FXa) inhibitor for venous thromboembolism
treatment. Recently, increasing evidence have reported the beneficial effects of rivaroxaban …
treatment. Recently, increasing evidence have reported the beneficial effects of rivaroxaban …
Cilostazol attenuates angiotensin II–induced abdominal aortic aneurysms but not atherosclerosis in apolipoprotein E–deficient mice
R Umebayashi, HA Uchida, Y Kakio… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Abdominal aortic aneurysm (AAA) is a permanent dilation of the abdominal aorta
associated with rupture, which frequently results in fatal consequences. AAA tissue is …
associated with rupture, which frequently results in fatal consequences. AAA tissue is …
Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization
OBJECTIVE: We sought to examine the effect of resveratrol (3, 4′, 5-trihydroxy-trans-
stilbene), a plant-derived polyphenolic compound, on the development of abdominal aortic …
stilbene), a plant-derived polyphenolic compound, on the development of abdominal aortic …