[HTML][HTML] Epigenetic regulation of peroxisome proliferator-activated receptor gamma mediates high-fat diet-induced non-alcoholic fatty liver disease
T Hajri, M Zaiou, TV Fungwe, K Ouguerram, S Besong - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in Western countries and has
become a serious public health concern. Although Western-style dietary patterns …
become a serious public health concern. Although Western-style dietary patterns …
[HTML][HTML] Peroxisome proliferator-activated receptor-γ as a target and regulator of epigenetic mechanisms in nonalcoholic fatty liver disease
M Zaiou - Cells, 2023 - mdpi.com
Peroxisome proliferator-activated receptor-γ (PPARγ) belongs to the superfamily of nuclear
receptors that control the transcription of multiple genes. Although it is found in many cells …
receptors that control the transcription of multiple genes. Although it is found in many cells …
[HTML][HTML] Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity
M Régnier, A Polizzi, S Smati, C Lukowicz… - Scientific reports, 2020 - nature.com
Peroxisome proliferator activated receptor α (PPARα) acts as a fatty acid sensor to
orchestrate the transcription of genes coding for rate-limiting enzymes required for lipid …
orchestrate the transcription of genes coding for rate-limiting enzymes required for lipid …
Loss of Hepatocyte‐Specific PPARγ Expression Ameliorates Early Events of Steatohepatitis in Mice Fed the Methionine and Choline‐Deficient Diet
J Cordoba-Chacon - PPAR research, 2020 - Wiley Online Library
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. To date,
there is not a specific and approved treatment for NAFLD yet, and therefore, it is important to …
there is not a specific and approved treatment for NAFLD yet, and therefore, it is important to …
[HTML][HTML] Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression
L Li, J Fu, D Liu, J Sun, Y Hou, C Chen, J Shao… - Redox biology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is an emerging global disease with increasing
prevalence. However, the mechanism of NAFLD development is not fully understood. To …
prevalence. However, the mechanism of NAFLD development is not fully understood. To …
Reduced expression of peroxisome proliferator‐activated receptor‐α may have an important role in the development of non‐alcoholic fatty liver disease
JE Yeon, KM Choi, SH Baik, KO Kim… - Journal of …, 2004 - Wiley Online Library
Background: Although the pathogenesis of non‐alcoholic fatty liver disease (NAFLD)
remains poorly understood, metabolic syndrome associated with insulin resistance is the …
remains poorly understood, metabolic syndrome associated with insulin resistance is the …
[HTML][HTML] Changes in peroxisome proliferator-activated receptor alpha target gene expression in peripheral blood mononuclear cells associated with non-alcoholic fatty …
TT Li, TB Tan, HQ Hou, XY Zhao - Lipids in health and disease, 2018 - Springer
Objective To identify differences in the expression of peroxisome proliferator-activated
receptor alpha (PPARα) target genes in human peripheral blood mononuclear cells …
receptor alpha (PPARα) target genes in human peripheral blood mononuclear cells …
[PDF][PDF] Novel aspects of PPARα‐mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study
Peroxisome proliferator‐activated receptor‐α (PPARα) is a major transcriptional regulator of
lipid metabolism. It is activated by diverse chemicals such as fatty acids (FAs) and regulates …
lipid metabolism. It is activated by diverse chemicals such as fatty acids (FAs) and regulates …
An increase in liver PPARγ2 is an initial event to induce fatty liver in response to a diet high in butter: PPARγ2 knockdown improves fatty liver induced by high …
T Yamazaki, S Shiraishi, K Kishimoto, S Miura… - The Journal of nutritional …, 2011 - Elsevier
The effects of a diet rich in saturated fat on fatty liver formation and the related mechanisms
that induce fatty liver were examined. C57BL/6J mice were fed butter or safflower oil as a …
that induce fatty liver were examined. C57BL/6J mice were fed butter or safflower oil as a …
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
A Montagner, A Polizzi, E Fouché, S Ducheix, Y Lippi… - Gut, 2016 - gut.bmj.com
Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor
expressed in tissues with high oxidative activity that plays a central role in metabolism. In …
expressed in tissues with high oxidative activity that plays a central role in metabolism. In …
相关搜索
- epigenetic regulation high fat
- epigenetic regulation liver disease
- high fat liver disease
- epigenetic regulation receptor gamma
- high fat receptor gamma
- receptor gamma liver disease
- epigenetic mechanisms receptor γ
- reduced expression liver disease
- high fat hepatic steatosis
- high fat nrf2 deficiency
- receptor α liver disease