Alterations in DNA methylation frequently occur in hepatocellular cancer (HCC). We have
previously demonstrated that hypermethylation in candidate genes can be detected in …

Epigenetic changes as well as genetic changes are mechanisms of tumorigenesis. We
aimed to identify novel genes that are silenced by DNA hypermethylation in hepatocellular …

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and has a
poor prognosis. Epigenetic modification has been shown to be deregulated during HCC …

To clarify genome‐wide DNA methylation profiles during hepatocarcinogenesis, bacterial
artificial chromosome (BAC) array‐based methylated CpG island amplification was …

Background Epigenetic alterations, such as aberrant DNA methylation of promoter and
enhancer regions, which lead to atypical gene expression, have been associated with …

Hepatocellular Carcinoma (HCC) is one of the most common cancers in the world and it is
often associated with poor prognosis. Liver transplantation and resection are two currently …

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is one of the most frequent
human cancers and a major cause of cancer-related death worldwide. The major risk factors …

Abberrant DNA methylation is one of the hallmarks of cancerogenesis. Our study aims to
delineate differential DNA methylation in cirrhosis and hepatic cancerogenesis. Patterns of …

Hepatocellular carcinoma (HCC) incidence has increased in the US and also has one of the
fastest growing death rates of any cancer. The purpose of the current study was to discover …

Background Hepatocellular carcinoma (HCC) is characterized by late detection and fast
progression, and it is believed that epigenetic disruption may be the cause of its molecular …