[HTML][HTML] CRISPR in context: towards a socially responsible debate on embryo editing
M Morrison, S de Saille - Palgrave Communications, 2019 - nature.com
Following the birth in 2018 of two babies from embryos altered using CRISPR-Cas9, human
germline gene editing (GGE) moved from abstract concern to reality. He Jiankui, the scientist …
germline gene editing (GGE) moved from abstract concern to reality. He Jiankui, the scientist …
The wisdom of germline editing: an ethical analysis of the use of CRISPR-Cas9 to edit human embryos
JM Gumer - The New Bioethics, 2019 - Taylor & Francis
With recent reports that a Chinese scientist used CRISPR-Cas9 to heritably edit the
genomes of human embryos (ie, germline editing) brought to term, discussions regarding …
genomes of human embryos (ie, germline editing) brought to term, discussions regarding …
Focusing on Human Rights: a framework for CRISPR germline genome editing ethics and regulation
abstract The late 2018 announcement of the claimed births of CRISPR-edited babies has
stimulated widespread condemnation and calls by some leading scientists for a moratorium …
stimulated widespread condemnation and calls by some leading scientists for a moratorium …
[HTML][HTML] Human germline interventions–think first
E Hildt - Frontiers in genetics, 2016 - frontiersin.org
Recent studies using gene editing tools such as CRISPR/Cas9 have shown an enormously
broad spectrum of possible future applications. This genetic engineering technique allows …
broad spectrum of possible future applications. This genetic engineering technique allows …
CRISPR babies: a view from the centre of the storm
R Lovell-Badge - Development, 2019 - journals.biologists.com
Towards the end of November 2018, news broke that the Chinese researcher He Jiankui
had created the world's first genome-edited babies. This came shortly before the start of the …
had created the world's first genome-edited babies. This came shortly before the start of the …
Ethics and germline gene editing
J Sugarman - EMBO reports, 2015 - embopress.org
The current kerfuffle around the use of CRISPR/Cas9 and other gene editing technologies in
human germline research is the latest in a series of related controversies at the intersection …
human germline research is the latest in a series of related controversies at the intersection …
[HTML][HTML] CRISPR-Cas and its wide-ranging applications: From human genome editing to environmental implications, technical limitations, hazards and bioethical …
R Piergentili, A Del Rio, F Signore, F Umani Ronchi… - Cells, 2021 - mdpi.com
The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …
including man. During the years this technique has been applied in several fields, such as …
[HTML][HTML] Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic
Abstract Following the Second Summit on Human Gene Editing in Hong Kong in 2018,
where the birth of two girls with germline genome editing was revealed, the need for a …
where the birth of two girls with germline genome editing was revealed, the need for a …
CRISPR/Cas9 genome editing–new and old ethical issues arising from a revolutionary technology
M Baumann - NanoEthics, 2016 - Springer
Although germline editing has been the subject of debate ever since the 1980s, it tended to
be based rather on speculative assumptions until April 2015, when CRISPR/Cas9 …
be based rather on speculative assumptions until April 2015, when CRISPR/Cas9 …
[HTML][HTML] # CRISPRbabies: notes on a scandal
SP Ryder - The CRISPR Journal, 2018 - liebertpub.com
Like almost everyone, I was stunned by the birth announcement of genetically modified
twins, Lulu and Nana. A Tweet pointed me to the MIT Technology Review scoop1 that, along …
twins, Lulu and Nana. A Tweet pointed me to the MIT Technology Review scoop1 that, along …