Human germline CRISPR-Cas modification: toward a regulatory framework

NH Evitt, S Mascharak, RB Altman - The American Journal of …, 2015 - Taylor & Francis
CRISPR germline editing therapies (CGETs) hold unprecedented potential to eradicate
hereditary disorders. However, the prospect of altering the human germline has sparked a …

A society-wide conversation is needed about germline genome editing using CRISPR

E Birney - Nature Medicine, 2024 - nature.com
A society-wide conversation is needed about germline genome editing using CRISPR | Nature
Medicine Skip to main content Thank you for visiting nature.com. You are using a browser …

No ethical divide between China and the West in human embryo research

X Zhai, V Ng, R Lie - Developing World Bioethics, 2016 - Wiley Online Library
This is a discussion of the reaction to the recent research article publication in the journal
Protein & Cell by a group of scientists at Sun Yat‐sen University using the CRISPR/Cas9 …

Avoiding the off-target effects of CRISPR/cas9 system is still a challenging accomplishment for genetic transformation

RH Herai - Gene, 2019 - Elsevier
The recent disclosure of a human embryo subjected to a genetic transformation using the
CRISPR/cas9 system give rise to several concerns on ethical questions about its …

Islamic perspectives on CRISPR/Cas9-mediated human germline gene editing: a preliminary discussion

NM Isa, NA Zulkifli, S Man - Science and engineering ethics, 2020 - Springer
The recent development of CRISPR/Cas9 technology has rekindled the ethical debate
concerning human germline modification that has begun decades ago. This inexpensive …

Bioethical issues in genome editing by CRISPR-Cas9 technology

FB Ayanoğlu, AE Elçin, YM Elçin - Turkish Journal of Biology, 2020 - journals.tubitak.gov.tr
Genome editing technologies have led to fundamental changes in genetic science. Among
them, CRISPR-Cas9 technology particularly stands out due to its advantages such as easy …

[图书][B] Human flourishing in an age of gene editing

E Parens, J Johnston - 2019 - books.google.com
International uproar followed the recent announcement of the birth of twin girls whose
genomes had been edited with a breakthrough DNA editing-technology. This technology …

Societal and ethical impacts of germline genome editing: How can we secure human rights?

J Halpern, SE O'Hara, KW Doxzen… - The CRISPR …, 2019 - liebertpub.com
Genome editing has opened up the possibility of heritable alteration of the human germline.
The potential of this powerful tool has spurred a call for establishing robust regulatory …

[图书][B] Altered inheritance: CRISPR and the ethics of human genome editing

F Baylis - 2019 - books.google.com
A leading bioethicist offers critical insights into the scientific, ethical, and political
implications of human genome editing. Designer babies, once found only in science fiction …

Limits of Responsibility: Genome Editing, Asilomar, and the Politics of Deliberation

JB Hurlbut - Hastings Center Report, 2015 - Wiley Online Library
Abstract On April 3, 2015, a group of prominent biologists and ethicists called for a
worldwide moratorium on human genetic engineering in which the genetic modifications …