The development and maturation of the immune system in zebrafish was investigated using
immune-related gene expression profiling by quantitative real-time polymerase chain …

The basal position of fish in vertebrate phylogeny makes them very attractive for genomic
and functional comparative immunity studies. Adaptive immunity arose early in vertebrate …

The zebrafish (Danio rerio) has been extensively used in biomedical research as a model to
study vertebrate development and hematopoiesis and recently, it has been adopted into …

Information on the ontogeny of the fish immune system is largely restricted to a few species
of teleosts (eg, rainbow trout, catfish, zebrafish, sea bass) and has previously focused on …

The work presented here reports the expression of immune-related genes during
ontogenesis in the oyster Crassostrea gigas. Expression patterns of 18 selected genes …

Cartilaginous fish express canonical B and T cell recognition genes, but their lymphoid
organs and lymphocyte development have been poorly defined. Here, the expression of Ig …

The closely linked recombination activating genes, rag1 and rag2, encode components of
the recombinase involved in V (D) J recombination of the immunoglobulin and T-cell …

The effectiveness of immunostimulation and vaccination of cultured fish heavily depends on
the degree of maturity of their immune system. In this review, we summarise the recent data …

The common denominator of the vertebrate immune system includes the antigen receptors
(immunoglobulins and TCR), the MHC molecules and the recombination activating genes …

Immune systems protect animals from threats by parasites, bacteria and viruses. Most of
what we know today about the composition, function and regulation of the two fundamental …