DNA methylation is evolutionarily conserved. Vertebrates exhibit high, widespread DNA
methylation whereas invertebrate genomes are less methylated, predominantly within gene …

DNA methylation is generally limited to CpG doublets located at the gene promoter with an
involvement in gene silencing. Surprisingly, two recent papers showed an extensive …

Background The role of epigenetic modifications such as DNA methylation during vertebrate
sexual development is far from being clear. Using the zebrafish model, we tested the effects …

DNA methylation is a common regulator of gene expression and development in
mammalian and other vertebrate genomes. DNA methylation has been studied so far in a …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA
methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is …

DNA methylation plays a vital role in tissue development and differentiation in eukaryotes.
Epigenetic studies have been seldom conducted in the extremely diverse and evolutionarily …

Cytosine DNA methylation is crucial for gene regulation and maintenance of genome
stability. However, the detailed nile tilapia methylome remains uncharacterized. In this study …

In vertebrates, epigenetic modifications influence gene transcription, and an appropriate
DNA methylation is critical in development. Indeed, a precise temporal and spatial pattern of …

DNA methylation occurs on cytosines, is catalyzed by DNA methyltransferases (DNMTs),
and is present at high levels in all vertebrates. DNA methylation plays essential roles in …