In France, the legal routes used to administer midazolam to a patient are intravenously and
intramuscularly. For anaesthetists, these routes are not well adapted to paediatric use; they …

A serum concentration profile study on midazolam in children was done. Fifty six children
aged 3–10 years took part. The routes investigated were intravenous, intramuscular, rectal …

The first‐dose pharmacokinetics of midazolam and its primary α‐hydroxy metabolite were
studied after single‐dose administration. Eligible study patients were enrolled into one of …

Twelve children 1-5 y old were randomly assigned to receive midazolam 0.2 mg. kg-1 either
by the intravenous (IV) or intranasal (IN) routes. After IN administration the rapid onset of …

The pharmacokinetics of midazolam and 1-hydroxymethylmidazolam were investigated
following oral administration of 7.5, 15 and 30 mg doses of midazolam in solution to 12 …

Aims Midazolam has good anxiolytic qualities and is a well established premedication agent
before anaesthesia or short surgical procedures. The objective of the present study was to …

Midazolam and 1-hydroxymidazolam plasma concentrations have been monitored and
pharmacokinetic parameters of midazolam estimated during anaesthesia induced and …

The pharmacokinetics of midazolam and of its main metabolite, 1-hydroxymidazolam, were
investigated in intensive care patients after intravenous bolus of 0.2 mg/kg followed by a 0.1 …

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo [1, 5-a][1, 4] benzodiazepine (midazolam,
Ro 21-3981, Dormicum) is a special type of benzodiazepine. Its salts are water-soluble and …

The extent of bioavailability of midazolam following sublingual and oral administration were
evaluated. Three healthy volunteers received a single iS-mg dose of midazolam maleate by …