Selective inhibition of the polymerase activity of DNA polymerase I. Further evidence for separate active sites for polymerase and 3'to 5'exonuclease activities
BG Que, KM Downey, AG So - Biochemistry, 1979 - ACS Publications
Benito G. Que, Kathleen M. Downey,* and Antero G. So* abstract: The chelating agent 1, 10-
phenanthroline, in the presence of a reducing agent, selectively inhibits the polymerase …
phenanthroline, in the presence of a reducing agent, selectively inhibits the polymerase …
DNA binding domain of Escherichia coli DNA polymerase I: identification of arginine-841 as an essential residue
PM Mohan, A Basu, S Basu, KI Abraham… - Biochemistry, 1988 - ACS Publications
Department of Biochemistry, UMDNJ-New Jersey Medical School, Newark, New Jersey
07103 Received April 21, 1987; Revised Manuscript Received September 10, 1987 …
07103 Received April 21, 1987; Revised Manuscript Received September 10, 1987 …
Binding of daunomycin to DNA and the inhibition of RNA and DNA synthesis
NS Mizuno, B Zakis, RW Decker - Cancer research, 1975 - AACR
With synchronized tissue culture cells (L929), daunomycin had the greatest inhibitory effect
on cell growth when the drug was administered during the later stages of cell division (late …
on cell growth when the drug was administered during the later stages of cell division (late …
[HTML][HTML] Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates ContainingN-acetyl-2-aminofluorene or N-2-aminofluorene adducts …
L Dzantiev, LJ Romano - Journal of Biological Chemistry, 1999 - ASBMB
DNA adducts formed by aromatic amines such asN-acetyl-2-aminofluorene (AAF) andN-2-
aminofluorene (AF) are known to cause mutations by interfering with the process of DNA …
aminofluorene (AF) are known to cause mutations by interfering with the process of DNA …
Differential sensitivity of low molecular weight DNA polymerase to sulfhydryl-blocking reagents
A Matsukage, EW Bohn, SH Wilson - … Acta (BBA)-Nucleic Acids and Protein …, 1975 - Elsevier
Activity of a 2.5 S mouse myeloma DNA polymerase (termed DNA polymerase II) measured
with either poly (rA) or poly (dA) as template did not require sulfhydryl-reducing reagents, but …
with either poly (rA) or poly (dA) as template did not require sulfhydryl-reducing reagents, but …
Development of novel inhibitor probes of DNA polymerase III based on dGTP analogs of the HPUra type: base, nucleoside and nucleotide derivatives of N 2 …
MM Butler, LW Dudycz, NN Khan… - Nucleic acids …, 1990 - academic.oup.com
(p-Hydroxyphenylhydrazino) uracil (H 2-HPUra) is a selective and potent inhibitor of the
replication-specific class III DNA polymerase (pol III) of Gr+ bacteria. Although formally a …
replication-specific class III DNA polymerase (pol III) of Gr+ bacteria. Although formally a …
Selective inhibition of the 3'to 5'exonuclease activity associated with DNA polymerases: a mechanism of mutagenesis
John J. Byrnes, 1 Kathleen M. Downey, § Benito G. Que, Marietta YW Lee, 11 Vicky L. Black,
and Antero G. So*·# abstract: The V to 5'exonuclease activity associated with both …
and Antero G. So*·# abstract: The V to 5'exonuclease activity associated with both …
[HTML][HTML] Further Characterization of HeLa DNA Polymerase∊(∗)
G Chui, S Linn - Journal of Biological Chemistry, 1995 - ASBMB
DNA polymerase∊(pol∊) from HeLa cells was purified to near homogeneity, utilizing Mono
S fast protein liquid chromatography for complete separation from pol α. The purified pol∊ …
S fast protein liquid chromatography for complete separation from pol α. The purified pol∊ …
Interaction of Escherichia coli DNA polymerase I with azidoDNA and fluorescent DNA probes: identification of protein-DNA contacts
CE Catalano, DJ Allen, SJ Benkovic - Biochemistry, 1990 - ACS Publications
Department of Chemistry, 152 Davey Laboratory, The Pennsylvania State University,
University Park, Pennsylvania 16802 Received September 5, 1989; Revised Manuscript …
University Park, Pennsylvania 16802 Received September 5, 1989; Revised Manuscript …
Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA.
CA Bonner, SK Randall, C Rayssiguier… - Journal of Biological …, 1988 - ASBMB
We have investigated the ability of DNA polymerases from SOS-induced and uninduced
Escherichia coli to incorporate nucleotides at a well-defined abasic (apurinic/apyrimidinic) …
Escherichia coli to incorporate nucleotides at a well-defined abasic (apurinic/apyrimidinic) …