Abdominal aortic aneurysm (AAA) is a common disease that, when surgical treatment is
inapplicable, results in rupture of the aorta with high mortality. Although nonsurgical …

Abdominal aortic aneurysm (AAA) is a common disease among elderly people that, when
surgical treatment is inapplicable, results in progressive expansion and rupture of the aorta …

Despite the advances in molecular cell biology, identification of a therapeutic target in a
given disease still poses a significant challenge. Here we report a strategy for identification …

Abdominal aortic aneurysm (AAA) is a common disease that causes progressive expansion
and rupture of the aorta with high mortality. There is a large and unmet need for nonsurgical …

Abdominal aortic aneurysm (AAA) is a common disease causing segmental expansion and
rupture of the aorta with a high mortality rate. The lack of nonsurgical treatment represents a …

Abdominal aortic aneurysm (AAA) is an asymptomatic, potentially lethal disease whose
ruptures have a high mortality rate. An effective pharmacological approach to decrease …

We have previously reported that activation of AMP-activated kinase alpha 2 (AMPKa2) by
nicotine or angiotensin II (AngII) instigates formation of abdominal aortic aneurysms (AAA) in …

Clinical evidence links increased aortic collagen content and stiffness to abdominal aortic
aneurysm (AAA) formation. However, the possibility that excess collagen contributes to AAA …

BACKGROUND: In humans, there is a 4: 1 male: female ratio in the incidence of abdominal
aortic aneurysms (AAAs). c-Jun-N-terminal kinase (JNK) is an important upstream regulator …

Abdominal aortic aneurysm (AAA) is characterized by at least 1.5-fold enlargement of the
infrarenal aorta, a ruptured AAA is life-threatening. Colchicine is a medicine used to treat …