SRA-domain proteins required for DRM2-mediated de novo DNA methylation

LM Johnson, JA Law, A Khattar, IR Henderson… - PLoS …, 2008 - journals.plos.org
De novo DNA methylation and the maintenance of DNA methylation in asymmetrical
sequence contexts is catalyzed by homologous proteins in plants (DRM2) and animals …

Identification of genes required for de novo DNA methylation in Arabidopsis

MVC Greenberg, I Ausin, SWL Chan, SJ Cokus… - Epigenetics, 2011 - Taylor & Francis
De novo DNA methylation in Arabidopsis thaliana is catalyzed by the methyltransferase
DRM2, a homolog of the mammalian de novo methyltransferase DNMT3. DRM2 is targeted …

Involvement of putative SNF2 chromatin remodeling protein DRD1 in RNA-directed DNA methylation

T Kanno, MF Mette, DP Kreil, W Aufsatz, M Matzke… - Current Biology, 2004 - cell.com
In plants, the mechanism by which RNA can induce de novo cytosine methylation of
homologous DNA is poorly understood. Cytosines in all sequence contexts become …

A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation

M Xie, G Ren, P Costa-Nunes, O Pontes… - Nucleic Acids …, 2012 - academic.oup.com
Plant specific SGS3-like proteins are composed of various combinations of an RNA-binding
XS domain, a zinc-finger zf-XS domain, a coil–coil domain and a domain of unknown …

A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation

Q Niu, Z Song, K Tang, L Chen, L Wang, T Ban… - Nature …, 2021 - nature.com
In plants, RNA-directed DNA methylation (RdDM) is a well-known de novo DNA methylation
pathway that involves two plant-specific RNA polymerases, Pol IV and Pol V. In this study …

SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV

JA Law, AA Vashisht, JA Wohlschlegel… - PLoS …, 2011 - journals.plos.org
DNA methylation is an evolutionarily conserved epigenetic modification that is critical for
gene silencing and the maintenance of genome integrity. In Arabidopsis thaliana, the de …

Molecular mechanism of action of plant DRM de novo DNA methyltransferases

X Zhong, J Du, CJ Hale, J Gallego-Bartolome, S Feng… - Cell, 2014 - cell.com
DNA methylation is a conserved epigenetic gene-regulation mechanism. DOMAINS
REARRANGED METHYLTRANSFERASE (DRM) is a key de novo methyltransferase in …

The de novo cytosine methyltransferase DRM2 requires intact UBA domains and a catalytically mutated paralog DRM3 during RNA–directed DNA methylation in …

IR Henderson, A Deleris, W Wong, X Zhong… - PLoS …, 2010 - journals.plos.org
Eukaryotic DNA cytosine methylation can be used to transcriptionally silence repetitive
sequences, including transposons and retroviruses. This silencing is stable between cell …

Regulatory link between DNA methylation and active demethylation in Arabidopsis

M Lei, H Zhang, R Julian, K Tang… - Proceedings of the …, 2015 - National Acad Sciences
De novo DNA methylation through the RNA-directed DNA methylation (RdDM) pathway and
active DNA demethylation play important roles in controlling genome-wide DNA methylation …

DNA methylation readers in plants

D Grimanelli, M Ingouff - Journal of Molecular Biology, 2020 - Elsevier
In plants, DNA methylation occurs in distinct sequence contexts, including CG, CHG, and
CHH. Thus, plants have developed a surprisingly diverse set of DNA methylation readers to …