Melatonin is a hormone produced mainly by the pineal gland in most vertebrate species,
including humans. Recent metabolic, receptor and functional studies created a picture of the …

Melatonin is an evolutionarily conserved molecule that serves a time-keeping function in
various species. In vertebrates, melatonin is produced predominantly by the pineal gland …

Melatonin (N-acetyl-5-methoxytryptamine) is an evolutionary highly conserved molecule that
plays an important role in conveying the clock and calendar information to all living …

Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Melatonin (N-acetyl-5-methoxytryptamine) was first purified and characterized from the
bovine pineal gland extract by Aron Lerner and co-workers in 1958. Since then, a plethora of …

The functional versatility and diversity of melatonin has exceeded everyone's expectations.
The evidence is substantial that melatonin has multiple receptor-mediated and receptor …

Melatonin is a ubiquitous molecule and widely distributed in nature, with functional activity
occurring in unicellular organisms, plants, fungi and animals. In most vertebrates, including …

Melatonin, a hormone produced primarily by the pineal gland, is also secreted from the gut
and eye during darkness. There are three classes of melatonin receptors, MT< sub> 1, MT< …

Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal
gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of …

Melatonin is a methoxyindole synthesized within the pineal gland. The hormone is secreted
during the night and appears to play multiple roles within the human organism. The …