The dopamine (DA) transporter DAT1 is a major target bound by cocaine in brain. We
examined the influence of functional genetic variants in DAT1 on cocaine addiction. Repeat …

Epistatic gene–gene interactions could contribute to the heritability of complex multigenic
disorders, but few examples have been reported. Here, we focus on the role of aberrant …

The dopamine transporter (DAT) provides major regulation of the synaptic levels of
dopamine and is a principal target of psychostimulant drugs. Associations between DAT …

Drug addiction is a complex neuropsychiatric disorder involving the environmental and
genetic factors. Genetic and physiological evidences suggest that the dopaminergic system …

Human dopamine transporter gene (DAT1) has a variable number of tandem repeats
(VNTR) in its 3′-untranslated region (UTR). The association between the VNTR …

A 40 base polymorphism of a variable number of tandem repeats (VNTR) has been
described in the 3′ untranslated region of the gene (SLC6A3) coding for the dopamine …

Individual variability in responses to stimulant drugs may influence risk of stimulant abuse
and treatment response. However, the genetic determinants of this variability have yet to be …

Genetic variation of the dopamine transporter gene (DAT1) is of particular interest in the
study of attention-deficit hyperactivity disorder (ADHD), since stimulant drugs interact directly …

The aim of our study was to investigate the potential association of dopamine receptor D2
gene (DRD2) TaqI RFLP A (rs1800497) and dopamine transporter gene (DAT) 3 …

Several groups have reported an association between the 10‐repeat allele of a dopamine
transporter (DAT1) 3′ UTR VNTR variant and ADHD but the finding has not been …