DNA methylation is an epigenetic modification of cytosines that undergoes dynamic
changes in a temporal, spatial and cell-type-specific manner. Recent advances in …

DNA methylation is a key epigenetic mark in the heritable regulation of gene expression,
with important roles in normal development and disease. Genomewide alterations in DNA …

As one of the most abundant and well-studied epigenetic modifications, DNA methylation
plays an essential role in normal development and cellular biology. Global alterations to the …

DNA methylation, a well-known epigenetic modification in mammalian genomes, is
important for development and health. Dysregulation of DNA methylation can cause …

DNA cytosine methylation is a central epigenetic modification which plays critical roles in
cellular processes including genome regulation, development and disease. Here, we review …

It is my great pleasure to introduce the third edition of DNA Methylation: Methods and
Protocols to the scientific and medical community. DNA methylation at cytosines forms one …

Alternative transcript isoforms are common in tumors and act as potential drivers of cancer.
Mechanisms determining altered isoform expression include somatic mutations in splice …

Simple Summary Aberrations of normal DNA methylation patterns are observed in many
cancers and are associated with chromatin alterations, changes in gene expression and …

In mammals, DNA methylation is a crucial epigenetic modification with key functions during
development. Cellular processes that are regulated by DNA methylation comprise X …

ABSTRACT DNA methylation is a highly conserved epigenetic modification that plays
essential roles in mammalian gene regulation, genome stability and development. Despite …