Distinct DNA methylation signatures, related to different prognosis, have been observed
across many cancers, including T-cell acute lymphoblastic leukemia (T-ALL), an aggressive …

Adult" T cell" acute lymphoblastic leukemia (T-ALL) is an aggressive hematological
malignancy that is associated with poor outcomes, requiring additional therapeutic options …

Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. AML is
a heterogeneous malignancy characterized by distinct genetic and epigenetic abnormalities …

Cancer cells undergo massive alterations in their DNA methylation patterns which result in
aberrant gene expression and malignant phenotypes. Abnormal DNA methylation is a …

The hallmark of acute lymphoblastic leukemia (ALL) is a progressive appearance of
malignant cell behavior that is triggered by the evolution of altered gene function. ALL has …

Acute myeloid leukemia (AML) is a heterogeneous disease that is characterized by distinct
cytogenetic or genetic abnormalities. Recent discoveries in cancer epigenetics …

Acute myeloid leukemia (AML) is characterized by molecular heterogeneity that is not fully
reflected in the current classification system. Recent insights point toward a significant role of …

Aberrant DNA methylation patterns are a characteristic feature of cancer including myeloid
malignancies such as acute myeloid leukemia (AML). The mechanisms behind aberrant …

Acute myeloid leukemia represents a heterogeneous malignant hematological disease with
a complex underlying biology suggesting multiple patterns of genetic and epigenetic …

DNA methylation is a dynamic process influencing gene expression by altering either coding
or non-coding loci. Despite advances in treatment of Acute Lymphoblastic Leukemia (ALL); …