Premedication with midazolam in young children: a comparison of four routes of administration

A Kogan, J Katz, R Efrat, LA Eidelman - Pediatric Anesthesia, 2002 - Wiley Online Library
Background: We undertook a study to determine the effects of four routes of administation on
the efficacy of midazolam for premedication. Methods: In a randomized double‐blind study …

Sublingual midazolam premedication in children: a dose response study

S Khalil, L Philbrook, M Rabb, K Wagner… - Pediatric …, 1998 - Wiley Online Library
The purpose of this study was to evaluate various doses of sublingual midazolam
premedication in children. In our prospective, double‐blind, placebo‐controlled trial …

Premedication of children with oral midazolam

CO McMillan, IA Spahr-Schopfer, N Sikich… - Canadian Journal of …, 1992 - Springer
In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of
oral midazolam premedication in children were evaluated in an ambulatory surgery unit …

Midazolam for premedication in children: nasal vs. rectal administration

C Lejus, M Renaudin, S Testa… - European journal of …, 1997 - Wiley Online Library
The authors compared the acceptance and efficacy of rectal and nasal administration of
midazolam (MDZ) for premedication. Ninety‐five ASA I and II paediatric patients (8 months to …

Intranasal midazolam for premedication of children undergoing day-case anaesthesia: comparison of two delivery systems with assessment of intra-observer …

N Griffith, S Howell, DG Mason - British journal of Anaesthesia, 1998 - Elsevier
Midazolam is often used for paediatric premedication. We have compared two methods of
administering midazolam intranasally in 44 surgical day-case children allocated randomly to …

Oral midazolam premedication for paediatric day case patients

SH Cray, JL Dixon, CMB Heard… - Pediatric …, 1996 - Wiley Online Library
Forty‐nine children having day‐stay surgical procedures were randomly assigned to receive
oral midazolam 0.75 mg· kg− 1 or placebo in a double blind fashion. The child's level of …

Oral midazolam in children: effect of time and adjunctive therapy

BC Weldon, MF Watcha, PF White - Anesthesia & Analgesia, 1992 - journals.lww.com
The purpose of this study was to determine the influence of timing and concomitant
administration of atropine and/or meperidine on the perioperative effects of oral midazolam …

Oral administration of midazolam as a premedicant for paediatric day‐case anaesthesia

A McCluskey, GH Meakin - Anaesthesia, 1994 - Wiley Online Library
Summary Fifty‐four children aged 1–10 years, scheduled for day‐case anaesthesia were
prescribed either oral midazolam 0.5 mg. kg‐1 or a placebo preparation 30‐60 min pre …

Oral midazolam preanesthetic medication in pediatric outpatients.

LH Feld, JB Negus, PF White - Anesthesiology, 1990 - europepmc.org
A need exists for a safe and effective oral preanesthetic medication for use in children
undergoing elective surgical procedures. We evaluated the effectiveness of three different …

Premedication with midazolam in children. Effect of intranasal, rectal and oral routes on plasma midazolam concentrations

JM Malinovsky, C Populaire, A Cozian… - …, 1995 - Wiley Online Library
We report a study performed to compare the time and plasma drug concentrations
necessary to achieve a similar state of sedation after midazolam premedication given by …