Extracellular vesicles, the cornerstone of next-generation cancer diagnosis?
Cancer has risen up to be a major cause of mortality worldwide over the past decades.
Despite advancements in cancer screening and diagnostics, a significant number of cancers …
Despite advancements in cancer screening and diagnostics, a significant number of cancers …
Monitoring therapy efficiency in cancer through extracellular vesicles
I Stevic, G Buescher, FL Ricklefs - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed vesicles
made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a …
made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a …
Extracellular vesicles in cancer—implications for future improvements in cancer care
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …
cell–cell communication within complex tissue environments. Such communication …
Towards the clinical implementation of extracellular vesicle-based biomarker assays for cancer
S Van Dorpe, P Tummers, H Denys… - Clinical Chemistry, 2024 - academic.oup.com
Background Substantial research has been devoted to elucidating the role of extracellular
vesicles (EVs) in the different hallmarks of cancer. Consequently, EVs are increasingly …
vesicles (EVs) in the different hallmarks of cancer. Consequently, EVs are increasingly …
Diagnostic and therapeutic potential of extracellular vesicles in B-cell malignancies
Extracellular vesicles (EV), comprising microvesicles and exosomes, are particles released
by every cell of an organism, found in all biological fluids, and commonly involved in cell-to …
by every cell of an organism, found in all biological fluids, and commonly involved in cell-to …
Extracellular vesicles as a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance
MH Vasconcelos, HR Caires, A Ābols… - Drug Resistance …, 2019 - Elsevier
Cancer-derived extracellular vesicles (EVs) have been detected in the bloodstream and
other biofluids of cancer patients. They carry various tumor-derived molecules such as …
other biofluids of cancer patients. They carry various tumor-derived molecules such as …
Role of extracellular vesicles in hematological malignancies
S Raimondo, C Corrado, L Raimondi… - BioMed research …, 2015 - Wiley Online Library
In recent years the role of tumor microenvironment in the progression of hematological
malignancies has been widely recognized. Recent studies have focused on how cancer …
malignancies has been widely recognized. Recent studies have focused on how cancer …
Extracellular vesicles in cancer: challenges and opportunities for clinical laboratories
Á González, S López-Borrego, A Sandúa… - Critical Reviews in …, 2024 - Taylor & Francis
Extracellular vesicles (EVs) are nano-sized particles secreted by most cells. They transport
different types of biomolecules (nucleic acids, proteins, and lipids) characteristic of their …
different types of biomolecules (nucleic acids, proteins, and lipids) characteristic of their …
Proteomic analysis of extracellular vesicles for cancer diagnostics
Extracellular vesicles (EVs) including exosomes and microvesicles are lipid bilayer‐
encapsulated nanoparticles released by cells, ranging from 40 nm to several microns in …
encapsulated nanoparticles released by cells, ranging from 40 nm to several microns in …
Optimization of ultracentrifugation‐based method to enhance the purity and proteomic profiling depth of plasma‐derived extracellular vesicles and particles
Circulating extracellular vesicles and particles (EVPs) are being investigated as potential
biomarkers for early cancer detection, prognosis, and disease monitoring. However, the …
biomarkers for early cancer detection, prognosis, and disease monitoring. However, the …