Integrative analysis of ChIP-chip and ChIP-seq dataset

LJ Zhu - Tiling arrays: Methods and protocols, 2013 - Springer
Epigenetic regulation and interactions between transcription factors and regulatory genomic
regions play crucial roles in controlling transcriptional regulatory networks that drive …

GTRD: a database on gene transcription regulation—2019 update

I Yevshin, R Sharipov, S Kolmykov… - Nucleic acids …, 2019 - academic.oup.com
The current version of the Gene Transcription Regulation Database (GTRD; http://gtrd.
biouml. org) contains information about:(i) transcription factor binding sites (TFBSs) and …

[HTML][HTML] From reads to insight: a hitchhiker's guide to ATAC-seq data analysis

F Yan, DR Powell, DJ Curtis, NC Wong - Genome biology, 2020 - Springer
Abstract Assay of Transposase Accessible Chromatin sequencing (ATAC-seq) is widely
used in studying chromatin biology, but a comprehensive review of the analysis tools has …

[HTML][HTML] Lisa: inferring transcriptional regulators through integrative modeling of public chromatin accessibility and ChIP-seq data

Q Qin, J Fan, R Zheng, C Wan, S Mei, Q Wu, H Sun… - Genome biology, 2020 - Springer
Abstract We developed Lisa (http://lisa. cistrome. org/) to predict the transcriptional
regulators (TRs) of differentially expressed or co-expressed gene sets. Based on the input …

[HTML][HTML] Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling

MP Meers, D Tenenbaum, S Henikoff - Epigenetics & chromatin, 2019 - Springer
Background CUT&RUN is an efficient epigenome profiling method that identifies sites of
DNA binding protein enrichment genome-wide with high signal to noise and low sequencing …

[HTML][HTML] Non-targeted transcription factors motifs are a systemic component of ChIP-seq datasets

R Worsley Hunt, WW Wasserman - Genome biology, 2014 - Springer
Background The global effort to annotate the non-coding portion of the human genome
relies heavily on chromatin immunoprecipitation data generated with high-throughput DNA …

[HTML][HTML] Evaluation of algorithm performance in ChIP-seq peak detection

EG Wilbanks, MT Facciotti - PloS one, 2010 - journals.plos.org
Next-generation DNA sequencing coupled with chromatin immunoprecipitation (ChIP-seq)
is revolutionizing our ability to interrogate whole genome protein-DNA interactions …

[HTML][HTML] ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic regions

NU Rashid, PG Giresi, JG Ibrahim, W Sun, JD Lieb - Genome biology, 2011 - Springer
Abstract ZINBA (Zero-Inflated Negative Binomial Algorithm) identifies genomic regions
enriched in a variety of ChIP-seq and related next-generation sequencing experiments …

ChIP-Enrich: gene set enrichment testing for ChIP-seq data

RP Welch, C Lee, PM Imbriano, S Patil… - Nucleic acids …, 2014 - academic.oup.com
Gene set enrichment testing can enhance the biological interpretation of ChIP-seq data.
Here, we develop a method, ChIP-Enrich, for this analysis which empirically adjusts for gene …

[HTML][HTML] ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline

Q Qin, S Mei, Q Wu, H Sun, L Li, L Taing, S Chen… - BMC …, 2016 - Springer
Background Transcription factor binding, histone modification, and chromatin accessibility
studies are important approaches to understanding the biology of gene regulation. ChIP-seq …