DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …

The possibility that alterations in DNA methylation are mechanistic drivers of development,
aging and susceptibility to disease is widely acknowledged, but evidence remains patchy or …

Experience‐dependent changes in DNA methylation can exert profound effects on neuronal
function and behaviour. A single learning event can induce a variety of DNA modifications …

DNA methylation is essential in brain function and behavior; therefore, understanding the
role of DNA methylation in brain-based disorders begins with the study of DNA methylation …

DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …

Depression is currently the leading cause of disability around the world. We conducted an
epigenome-wide association study (EWAS) in a sample of 58 depression score-discordant …

Monozygotic (MZ) twin studies constitute a key resource for the dissection of environmental
and biological risk factors for human complex disorders. Given that epigenetic differences …

MRI has enhanced our capacity to understand variations in brain structure and function
conferred by the genome. We identified 60 studies that report associations between DNA …

Tissue differences are one of the largest contributors to variability in the human DNA
methylome. Despite the tissue-specific nature of DNA methylation, the inaccessibility of …

Background One of the major challenges in current psychiatric epigenetic studies is the
tissue specificity of epigenetic changes since access to brain samples is limited. Peripheral …